The deuterated glucose insulin tolerance test:a new tool to delineate insulin-stimulated glucose uptake from suppression of endogenous glucose production  

作　　者：Christian A.Unger Marion C.Hope Ⅲ Michael Chase Kettering Cassidy E.Socia Barton C.Rice Darya S.Niamira William E.Cotham Reilly T.Enos 

机构地区：[1]Department of Pathology,Microbiology,and Immunology,University of South Carolina-School of Medicine,Columbia,SC 29029,United States [2]Department of Chemistry and Biochemistry,College of Arts and Science,University of South Carolina,Columbia,SC 29208,United States

出　　处：《Life Metabolism》2025年第1期51-55,共5页生命代谢(英文)

基　　金：supported by the grants K01-AT010348(National Institutes of Health-National Center for Complementary and Integrative Health);the University of South Carolina Advanced Support for Innovative Research Excellence(ASPIRE)to R.T.E.

摘　　要：Dear Editor,Assessing insulin responsiveness is crucial for understanding the underlying molecular mechanisms that contribute to disruptions in glucose metabolism.In preclinical research,glucose tolerance tests(GTTs)and insulin tolerance tests(ITTs)are widely regarded as essential tools due to their simplicity and affordability in assessing glucose homeostasis[1,2].

关 键 词：ENDOGENOUS HOMEOSTASIS clinical 

分 类 号：R335.6[医药卫生—人体生理学]