单孔与多孔胸腔镜肺癌根治术治疗非小细胞肺癌的效果对比  

Comparison of Single-port and Multi-port Thoracoscopic Radical Resection for Non-Small Cell Lung Cancer

作　　者：彭鹤云 张辉 徐涛 Peng Heyun;Zhang Hui;Xu Tao(Department of Thoracic Surgery,Changzhou Jintan District Hospital of Traditional Chinese Medicine,Changzhou 213200,Jiangsu Province,China)

机构地区：[1]常州市金坛区中医医院胸外科,江苏常州213200

出　　处：《中外医药研究》2025年第5期66-68,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:对比采用单孔与多孔胸腔镜肺癌根治术治疗非小细胞肺癌的效果。方法:按照随机数字表法,将常州市金坛区中医医院2021年3月—2024年3月收治的60例非小细胞肺癌患者分为单孔组(30例)和多孔组(30例)。单孔组采用单孔胸腔镜肺癌根治术治疗,多孔组采用多孔胸腔镜肺癌根治术治疗。对比两组围术期相关指标、炎性因子、并发症发生情况。结果:两组淋巴结清扫数量对比,差异无统计学意义(P>0.05);与多孔组比较,单孔组手术时间更长、术中出血量更少、住院时间更短(P<0.05)。术后2 d,两组C反应蛋白、白细胞介素-6以及肿瘤坏死因子-α水平升高,多孔组较单孔组高(P<0.05)。两组并发症发生率比较,差异无统计学意义(P>0.05)。结论:与多孔胸腔镜肺癌根治术相比,单孔胸腔镜肺癌根治术耗时稍长,但其术中出血量更少、患者住院时间更短,可减轻术后炎性反应,不会增加并发症发生风险。Objective:To compare the efficacy of single-port and multi-port thoracoscopic radical resection in the treatment of non-small cell lung cancer.Methods:Sixty patients with non-small cell lung cancer admitted to Changzhou Jintan District Hospital of Traditional Chinese Medicine from March 2021 to March 2024 were randomly divided into a single-port group(n=30)and a multi-port group(n=30)using a random number table.The single-port group underwent single-port thoracoscopic radical resection,while the multi-port group underwent multi-port thoracoscopic radical resection.Perioperative indicators,inflammatory factors,and complications were compared between the two groups.Results:There was no significant difference in the number of lymph nodes dissected between the two groups(P>0.05).Compared with the multi-port group,the single-port group had a longer operative time,less intraoperative blood loss,and a shorter hospital stay(P<0.05).Two days postoperatively,the levels of C-reactive protein,interleukin-6,and tumor necrosis factor-αincreased in both groups,with higher levels observed in the multi-port group compared to the single-port group(P<0.05).There was no significant difference in the incidence of complications between the two groups(P>0.05).Conclusion:Compared with multi-port thoracoscopic radical resection,single-port thoracoscopic radical resection takes slightly longer but results in less intraoperative blood loss,a shorter hospital stay,and reduced postoperative inflammatory response without increasing the risk of complications.

关 键 词：非小细胞肺癌 单孔胸腔镜肺癌根治术 多孔胸腔镜肺癌根治术 炎性因子 术中出血量 

分 类 号：R734.2[医药卫生—肿瘤]