两种手术方式治疗早期子宫内膜癌患者的效果对比  

Comparison of Effects of Two Surgical Methods in the Treatment of Patients with Early Endometrial Cancer

作　　者：欧大芬 梁永 OU Dafen;LIANG Yong(The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang 550001,China;不详)

机构地区：[1]贵州中医药大学第一附属医院,贵州贵阳550001

出　　处：《中外医学研究》2025年第7期134-137,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:对比两种手术方式治疗早期子宫内膜癌患者的效果。方法:选取2022年6月—2023年12月贵州省中医药大学第一附属医院收治的61例早期子宫内膜癌患者作为研究对象,根据不同手术方式将患者分为对照组(n=30,传统开腹手术)与观察组(n=31,腹腔镜手术)。比较两组术后恢复情况、并发症、炎症介质水平。结果:观察组术后肛门排气时间、术后下床活动时间、术后住院时间较对照组更短,女性性功能量表(female sexual function index,FSFI)评分较对照组更高,术后并发症率较对照组低,差异有统计学意义(P<0.05);术后,两组C反应蛋白(C-reactive protein,CRP)、白细胞介素-6(interleukin-6,IL-6)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)水平较术前升高,但观察组较对照组更低,差异有统计学意义(P<0.05)。结论:与传统开腹手术相比,腹腔镜手术治疗早期子宫内膜癌患者效果显著,可降低术后炎症介质水平,减少下肢深静脉血栓形成等并发症,缩短住院时间,促进术后尽快恢复。Objective:To compare the effects of two surgical methods in the treatment of patients with early endometrial cancer.Method:A total of 61 patients with early endometrial cancer who admitted to the First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine from June 2022 to December 2023 were selected as the research objects,the patients were divided into the control group(n=30,traditional open surgery)and the observation group(n=31,laparoscopic surgery)according to different surgical methods.The postoperative recovery,complications and levels of inflammatory mediators were compared between two groups.Result:The postoperative anal exhaust time,postoperative ambulation time and postoperative hospital stay in the observation group were shorter than those in the control group,the female sexual function index(FSFI)score was higher than that in the control group,and the postoperative complication rate was lower than that in the control group,the differences were statistically significant(P<0.05);after operation,the levels of C-reactive protein(CRP),interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)in two groups were higher than those before operation,but those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion:Compared with traditional open surgery,laparoscopic surgery is effective in the treatment of patients with early endometrial cancer,it can reduce the levels of postoperative inflammatory mediators,reduce complications such as deep venous thrombosis of lower limbs,shorten the length of hospital stay,and promote postoperative recovery as soon as possible.

关 键 词：开腹手术 腹腔镜手术 早期子宫内膜癌 术后恢复情况 炎症介质 

分 类 号：R737.33[医药卫生—肿瘤]