胸部CT放射组学在慢性阻塞性肺疾病中的研究进展  

Research progress of chest computed tomography radiomics applied to chronic obstructive pulmonary disease

作　　者：黄素银 吴繁[1] 周坤宁 邓宇[2] 王平 周玉民[1] Huang Suyin;Wu Fan;Zhou Kunning;Deng Yu;Wang Ping;Zhou Yumin(Department of Respiratory and Critical Care Medicine,the First Affiliated Hospital of Guangzhou Medical University,Guangzhou Institute of Respiratory Health,State Key Laboratory of Respiratory Disease,National Center for Respiratory Medicine,National Clinical Research Center for Respiratory Disease,Guangzhou 510120,China;Department of Radiology,the First Affiliated Hospital of Guangzhou Medical University,Guangzhou 510120,China;Hangzhou Smart Intelligent Co.Ltd.,Hangzhou 311121,China)

机构地区：[1]广州医科大学附属第一医院呼吸与危重症医学科,广州呼吸健康研究院,呼吸疾病全国重点实验室,国家呼吸医学中心,国家呼吸系统疾病临床医学研究中心,广州510120 [2]广州医科大学附属第一医院放射科,广州510120 [3]杭州时迈智能技术有限公司,杭州311121

出　　处：《国际呼吸杂志》2025年第2期167-172,共6页International Journal of Respiration

基　　金：呼吸疾病全国重点实验室临床及流行病学研究专项(SKLRD-L-202402);广州国家实验室自立项目(SRPG22-016、SRPG22-018);广州医科大学科研能力提升计划重大临床研究项目(GMUCR2024-01012)。

摘　　要：放射组学是从医学影像中高通量提取定量特征描述疾病表型的一个新兴技术。胸部CT放射组学可以全面量化肺部细微病理改变,有助于慢性阻塞性肺疾病(慢阻肺病)的早期诊治和管理,因此成为目前慢阻肺病评估和监测的研究热点之一。本文主要就胸部CT放射组学的主要工作流程,在识别慢阻肺病前期、筛查慢阻肺病、评估疾病进展中的作用,以及在慢阻肺病应用中所面临的挑战等方面予以综述。Radiomics is an emerging technology that describes disease phenotypes using the high-throughput extraction of quantitative features from medical imaging.Chest computed tomography(CT)radiomics allows for the comprehensive quantification of subtle pathological changes in the lungs,which aids in the early diagnosis,treatment,and management of chronic obstructive pulmonary disease(COPD).As a result,it has become a significant research focus in the assessment and monitoring of COPD.This article primarily discussed the main workflow of chest CT radiomics,its role in identifying pre-COPD,screening for COPD,and evaluating disease progression,as well as the challenges faced in its application to COPD.

关 键 词：肺疾病 慢性阻塞性 胸部CT 放射组学 

分 类 号：R73[医药卫生—肿瘤]