保留比值受损肺功能人群研究进展  

Research progress in the population of preserved ratio impaired spirometry

作　　者：唐娟 曹伟涛 莫泽洵 何桦[2] 赵祝香[2] Tang Juan;Cao Weitao;Mo Zexun;He Hua;Zhao Zhuxiang(The First Clinical Medical College,Guangdong Medical University,Zhanjiang 524000,China;Department of Pulmonary and Critical Care Medicine,Guangzhou First People′s Hospital,Guangzhou 510000,China)

机构地区：[1]广东医科大学第一临床医学院,湛江524000 [2]广州市第一人民医院呼吸与危重症医学科,广州510000

出　　处：《国际呼吸杂志》2025年第2期173-177,共5页International Journal of Respiration

基　　金：国家自然科学基金(82270041)。

摘　　要：2023年慢性阻塞性肺疾病全球创议首次提出保留比值受损肺功能(PRISm)的概念。PRISm是一种异质性且不稳定的表型,此类人群是发展为慢性阻塞性肺疾病的高危人群,与肺癌发生风险的增加及肺癌不良预后相关。目前在临床上该疾病关注度不高,本综述旨在探讨PRISm的流行病学、发生机制、临床特征、危险因素、疾病纵向转化,以及与肺癌相关性等情况,帮助临床医生和研究人员全面了解PRISm,以促进PRISm管理及诊疗的发展。The concept of preserved ratio impaired spirometry(PRISm)was initially introduced by the global initiative for chronic obstructive lung disease in 2023.PRISm is a heterogeneous and often unstable disease state,and such populations are at high risk of developing chronic obstructive pulmonary disease.It is associated with an increased risk of lung cancer development and a poor prognosis for lung cancer.Currently,PRISm has been less concerned.This review aims to explore the epidemiology,mechanisms,clinical features,risk factors,longitudinal transformation,and correlation with lung cancer of PRISm,thus providing a comprehensive and up-to-date understanding of PRISm to clinicians and researchers,and facilitating the development of management and diagnosis of PRISm.

关 键 词：肺疾病 慢性阻塞性 保留比值受损肺功能 肺功能 疾病管理 

分 类 号：R73[医药卫生—肿瘤]