常规超声及血流信号外延在术前预测甲状腺乳头状癌被膜外侵犯的价值  

Value of Conventional Ultrasound and Blood Flow Signal Epitaxy in Predicting Extraperinal Invasion of Papillary Thyroid Carcinoma Before Surgery

作　　者：杨爽灵 郑兰兰 李志岗 YANG Shuangling;ZHENG Lanlan;LI Zhigang(Pingmei Shenma Medical Group General Hospital,Pingdingshan,467000)

机构地区：[1]平煤神马医疗集团总医院,467000

出　　处：《实用癌症杂志》2025年第3期507-511,共5页The Practical Journal of Cancer

摘　　要：目的 探讨常规超声及血流信号外延在术前预测甲状腺乳头状癌被膜外侵犯的价值。方法 选取84例甲状腺乳头状癌患者临床资料,据术后病理诊断结果分组,被膜外侵犯组(38例)和被膜外未侵犯组(46例)。比较2组术前常规超声与血流信号外延检查结果,分析其对被膜外侵犯的诊断价值。结果 被膜外侵犯组结节最大径及形态不规则、边界模糊、纵横比>1、血流信号外延占比均大于被膜外未侵犯组,但钙化占比小于被膜外未侵犯组(P<0.05)。logistic回归分析显示,结节最大径、形态不规则、边界模糊、纵横比>1、钙化、血流信号外延是影响甲状腺乳头状癌被膜外侵犯的重要因素(P<0.05)。受试者工作特征(receiver operating characteristic curve, ROC)曲线显示,常规超声参数联合血流信号外延在术前预测甲状腺乳头状癌被膜外侵犯的曲线下面积(area under the curve, AUC)、敏感度、特异度分别为0.981、86.80%、95.65%,均大于常规超声参数及血流信号外延单一预测(P<0.05)。结论 常规超声联合血流信号外延在术前预测甲状腺乳头状癌被膜外侵犯的效能较高。Objective To investigate the value of conventional ultrasound and blood flow signal epitaxy in predicting extracaptival invasion of papillary thyroid carcinoma before surgery.Methods Clinical data of 84 patients with papillary thyroid carcinoma were selected,they were divided into 2 groups based on postoperative pathological diagnosis:extracapsular invasion group(38 cases)and extracapsular non invasion group(46 cases).The preoperative routine ultrasound and blood flow signal extension examination results were compared,their diagnostic value for extracapsular invasion were analyzed.Results The maximum diameter and irregular shape of nodules in the group with extracapsular invasion,blurred boundaries,aspect ratio>1,and the proportion of blood flow signal extension were all greater than those in the group without extracapsular invasion,but the proportion of calcification was smaller than that in the group without extracapsular invasion(P<0.05).Logistic regression analysis showed that the maximum diameter,irregular shape,blurred boundary,aspect ratio>1,calcification,and blood flow signal extension of nodules were important influencing factors on the invasion of papillary thyroid carcinoma beyond the capsule(P<0.05).The receiver operating characteristic curve(ROC)curve of the subjects showed that the area under the curve(AUC),sensitivity,and specificity of preoperative prediction of thyroid papillary carcinoma extracapsular invasion using conventional ultrasound parameters combined with blood flow signal extension were 0.981,86.80%,and 95.65%,respectively,all greater than those predicted by conventional ultrasound parameters and blood flow signal extension alone(P<0.05).Conclusion Conventional ultrasound combined with blood flow signal epitaxy has a high predictive effect on extraperinal invasion of papillary thyroid carcinoma before surgery.

关 键 词：常规超声 血流信号外延 手术 甲状腺乳头状癌 被膜外侵犯 

分 类 号：R736.1[医药卫生—肿瘤]