Uncovering the immune evasion mechanism of microbial pathogens: lessons from anti-encapsulation strategies adopted by a fungus  

作　　者：Jing WEI Yuxin ZHANG Letian XU 

机构地区：[1]School of Life Sciences,Suzhou Medical College of Soochow University,Suzhou,Jiangsu,China [2]State Key Laboratory of Biocatalysis and Enzyme Engineering,School of Life Sciences,Hubei University,Wuhan,China

出　　处：《Integrative Zoology》2024年第6期1229-1232,共4页整合动物学(英文版)

基　　金：supported by the National Natural Science Foundation of China(Grant no.32370523);Suzhou Medical College of Soochow University(Grant no.MP13405523).

摘　　要：Insect pests possess an effective innate immune system consisting of cellular and humoral facets that operate in a more or less coordinated way to protect against invading pathogens(Ma et al.2024).As a counter-strategy,pathogens have evolved numerous mechanisms to overcome the innate immune response(Eleftherianos et al.2022;Yang et al.2024).Therefore,the success of microbial pathogen-derived insecticides essentially depends on their ability to effectively and efficiently overcome the host immune pressure for propagation(Liu et al.2017;Tu et al.2023).A great variety of pathogens have specialized to infect insect pests,and many have been utilized as bio-insecticides in agronomic pest management,such as the entomopathogenic fungal genera Metarhizium and Beauveria for control of lepidopteran and coleopteran pests(Meyling&Eilenberg 2007).However,these existing measures are insufficient for the efficient control of the vast populations of insect pests.

关 键 词：OVERCOME mechanism utilized 

分 类 号：Q96[生物学—昆虫学]