Cancer situation in China:an analysis based on the global epidemiological data released in 2024  

作　　者：Xiayao Diao Chao Guo Yukai Jin Bowen Li Xuehan Gao Xin Du Zhenchong Chen Minju Jo Yi Zeng Chao Ding Wenwu Liu Jianrong Guo Shanqing Li Haibo Qiu 

机构地区：[1]Department of Thoracic Surgery,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,P.R.China [2]Department of Gastric Surgery,State Key Laboratory of Oncology in South China,Guangdong Provincial Clinical Research Center for Cancer,Sun Yat-sen University Cancer Center,Guangzhou,Guangdong,P.R.China

出　　处：《Cancer Communications》2025年第2期178-197,共20页癌症通讯(英文)

基　　金：National Postdoctoral Innovation Talent Support Program,Grant/Award Number:BX20240042;National High-Level Hospital Clinical Research Funding,Grant/Award Number:2022-PUMCH-B-011;Natural Science Foundation of Guangdong Province,Grant/Award Number:2022A1515012347;Beijing CSCO research fund,Grant/Award Number:Y-2019Roche-157。

摘　　要：Background:Cancer remains a major cause of mortality and a significant economic burden in China.Exploring the disparities in cancer patterns and control strategies between China and developed countries may offer valuable insights for policy formulation and enhance cancer management efforts.This study examined the incidence,mortality,and disability-adjusted life year(DALY)burden of cancer in China,and compared these metrics with those observed in the United States(US)and the United Kingdom(UK).Methods:Data on cancer incidence,mortality,and DALYs for China,the US,and the UK were sourced from the GLOBOCAN 2022 online database and the Global Burden of Disease 2021 study(GBD 2021).We utilized Joinpoint regression models to analyze trends in cancer incidence and mortality across these countries,calculating annual percent changes(APCs)and determining the optimal joinpoints.Results:In 2022,China recorded around 4,824,703 new cancer cases and 2,574,176 cancer-related deaths,contributing to 71,037,170 DALYs.China exhibited a lower cancer incidence rate compared to the US and the UK.Although cancer-related mortality in China is slightly lower than that in the UK,it is significantly higher than that in the US.Additionally,China experienced significantly higher DALY rates compared to both the US and UK.The cancer landscape in China was also undergoing significant changes,with a rapid rise in the incidence and burden of lung,colorectal,breast,cervical,and prostate cancers.Meanwhile,the incidence and burden of stomach cancer continued to decline.Although the incidence of liver and esophageal cancers was decreasing,the burden of liver cancer was increasing,while the burden of esophageal cancer remained largely unchanged.Conclusions:The cancer profile of China is shifting from that of a developing country to one more typical of a developed country.The ongoing population aging and the rise in unhealthy lifestyles are expected to further escalate the cancer burden in China.Consequently,it is crucial for Chinese authorities to revis

关 键 词：cancer pattern China disability-adjusted life year GBD 2021 GLOBOCAN 2022 INCIDENCE mortality risk factor United Kingdom United States 

分 类 号：R73[医药卫生—肿瘤]