肺结节良恶性诊断中动态增强磁共振成像定量分析的应用价值  

Exploring the application value of dynamic-enhanced magnetic resonance imaging quantitative analysis in the diagnosis of benign and malignant lung nodules

作　　者：李琰 郭洋洋 周青[1] Li Yan;Guo Yangyang;Zhou Qing(the First Affiliated Hospital of Henan University,Kaifeng 475000,China)

机构地区：[1]河南大学第一附属医院,开封475000

出　　处：《实用医技杂志》2025年第2期112-115,共4页Journal of Practical Medical Techniques

摘　　要：目的探讨肺结节良恶性诊断中动态增强磁共振成像(DCE-MRI)定量分析的应用价值。方法回顾性分析2023年1月至12月在我院进行CT及DCE-MRI检查的肺结节患者共计92例为研究对象,患者均在接受CT及DCE-MRI后进行穿刺病理活检。以穿刺病理活检的结果对患者肺结节的良恶性进行确诊,分析DCE-MRI对肺结节良恶性诊断的诊断价值。结果病理检测结果显示,良性49例,恶性43例;恶性结节体积运输常数(Ktrans)、血液回流常数(Kep)、血管外细胞外间隙体积系数(Ve)、造影剂体积比例(Vp)等DCE-MRI定量分析参数均大于良性结节(P<0.05);Ktrans、Kep、Ve、Vp诊断鉴别良性与恶性肺结节的曲线下面积(AUC)分别为0.779、0.792、0.726、0.657;DCE-MRI在对肺结节良恶性诊断的灵敏度95.4%(41/43)、特异度98.0%(48/49)、准确度96.7%(89/92)均高于CT检验方法的灵敏度79.1%(34/43)、特异度79.6%(39/49)、准确度79.4%(73/92)(P<0.05)。结论DCE-MRI定量分析可有效对肺结节良恶性进行诊断,Ktrans、Kep值对良恶性肺结节也具有一定的诊断价值。Objective To explore the application value of quantitative analysis of dynamic-enhanced magnetic resonance imaging(DCE-MRI)in the diagnosis of benign and malignant diagnosis of lung nodules.Methods A total of 92 patients with lung nodules who underwent CT and DCE-MRI from January 2023 to December 2023 were retrospectively analyzed in our hospital,and all patients underwent puncture pathology biopsy after undergoing CT and DCE-MRI.The benign and malignant nature of the lung nodules of the patients was confirmed with the results of puncture pathology biopsy,and the diagnostic value of DCE-MRI for the diagnosis of benign and malignant lung nodules.Results The results of pathological testing showed that there were 49 cases of benign and 43 cases of malignant;the quantitative analysis parameters of DCE-MRI such as Ktrans,Kep,Ve,and Vp of malignant nodules were greater than those of benign nodules(P<0.05);the AUCs for diagnosis of distinguishing benign and malignant lung nodules by Ktrans,Kep,Ve,and Vp were 0.779,0.792,0.726 and 0.657,respectively.The results showed that DCE-MRI had a higher sensitivity of 95.4%(41/43),specificity of 98.0%(48/49),accuracy 96.7%(89/92)than CT test of 79.1%(34/43),79.6%(39/49),and 79.4%(73/92)(P<0.05).Conclusion DCE-MRI quantitative analysis can effectively diagnose the benign and malignant lung nodules,and Ktrans and Kep values also have certain diagnostic value for benign and malignant lung nodules.

关 键 词：多发性肺结节 癌 磁共振成像 诊断 

分 类 号：R73[医药卫生—肿瘤]