不同运动方式对非酒精性脂肪肝合并肥胖人群的影响  

Effect of different exercise modes on people with nonalcoholic fatty liver disease and obesity

作　　者：曹永 伯秦霞 曹利 江蓉 易龙 CAO Yong;BO Qin-xia;CAO Li;JIANG Rong;YI Long(Department of Hepatobiliary Surgery,First Affiliated Hospital of Army Medical University,Chongqing 400038,China;Physical Examination Center,First Affiliated Hospital of Army Medical University,Chongqing 400038,China;Department of Military Nutrition and Food Hygiene,Department of Military Preventive Medicine,Army Medical University,Chongqing 400038,China)

机构地区：[1]陆军军医大学第一附属医院肝胆外科,重庆400038 [2]陆军军医大学第一附属医院体检中心,重庆400038 [3]陆军军医大学军事预防医学系军队营养与食品卫生学教研室,重庆400038

出　　处：《局解手术学杂志》2025年第3期254-258,共5页Journal of Regional Anatomy and Operative Surgery

基　　金：重庆市体育局科研项目(C202207)。

摘　　要：目的探讨不同运动方式对非酒精性脂肪肝(NAFLD)合并肥胖人群的影响,为该类人群的康复治疗提供运动处方参考。方法选取2023年1-9月在陆军军医大学第一附属医院体检中心通过健康筛查确诊为NAFLD合并肥胖的患者,采用随机数字表法分成3组,每组52例。有氧组患者进行有氧运动干预,抗阻组患者进行抗阻运动干预,联合组患者进行有氧+抗阻联合运动干预,持续12周。在干预前后,分别检测并比较各组患者的肝功能指标[包括丙氨酸转氨酶(ALT)、γ-谷氨酰转移酶(GGT)、天冬氨酸转氨酶(AST)、白蛋白、胆红素]、BMI、腰围、血糖及三酰甘油(TG)水平,分析不同运动方式对NAFLD合并肥胖患者各指标的改善效果。结果干预后,各组患者的BMI和腰围均显著下降(P<0.05);联合组的ALT、GGT、白蛋白、胆红素、TG和血糖较干预前显著改善(P<0.05)。抗阻运动对ALT、GGT、AST和TG的改善效果优于有氧运动(P<0.05),但对白蛋白、胆红素、BMI、腰围和血糖的改善效果与有氧运动相比无统计学差异(P>0.05);有氧+抗阻联合运动对BMI、腰围、白蛋白、胆红素和TG的改善效果优于单纯的抗阻运动和有氧运动(P<0.05),但对ALT、GGT和AST的改善效果与单纯抗阻运动无统计学差异(P>0.05)。结论针对NAFLD合并肥胖人群,建议采用有氧运动+抗阻联合运动的干预策略,可改善患者的肝功能、体脂分布及相关代谢指标,获得更优的治疗效果。Objective To investigate the effect of different exercise modes on people with nonalcoholic fatty liver disease(NAFLD)and obesity,thereby providing evidence-based exercise prescriptions for the rehabilitation of this population.Methods Patients diagnosed with NAFLD and obesity through health screenings at the Physical Examination Center of First Affiliated Hospital of Army Medical University from January to September 2023 were selected and assigned into three groups by random number table method,with 52 cases in each group.The aerobic group underwent aerobic exercise,the resistance group underwent resistance exercise,and the combined group underwent a combination of aerobic and resistance exercise for a duration of 12 weeks.The liver function indicators[including alanine aminotransferase(ALT),gamma-glutamyl transferase(GGT),aspartate aminotransferase(AST),albumin,and bilirubin],BMI,waist circumference,blood glucose,and triglyceride(TG)levels in each group were detected and compared.The improvement effect of different exercise modes on the above various indexes in patients with NAFLD and obesity was analyzed.Results After intervention,BMI and waist circumference were significantly decreased in each group(P<0.05);and the ALT,GGT,albumin,bilirubin,TG and blood glucose of the combined group were significantly improved compared with those before intervention(P<0.05).Resistance exercise had a better improvement effect on the ALT,GGT,AST and TG than aerobic exercise(P<0.05),while which had no significant difference in the albumin,bilirubin,BMI,waist circumference or blood glucose compared with aerobic exercise(P>0.05).The improvement effects of aerobic+resistance combined exercise on the BMI,waist circumference,albumin,bilirubin and TG were better than those of aerobic exercise and resistance exercise alone(P<0.05),while which had no significant difference in the improvement of the ALT,GGT or AST compared with resistance exercise alone(P>0.05).Conclusion For people with NAFLD and obesity,a combined aerobic and resistanc

关 键 词：非酒精性脂肪肝 肥胖 有氧运动 抗阻运动 

分 类 号：R575.5[医药卫生—消化系统] R589.2[医药卫生—内科学] G804.5[医药卫生—临床医学] G806[文化科学—运动人体科学]