机构地区:[1]上海市静安区中心医院普外科,上海200063
出 处:《中华普外科手术学杂志(电子版)》2025年第2期149-152,共4页Chinese Journal of Operative Procedures of General Surgery(Electronic Edition)
基 金:国家自然科学基金青年项目(82002804)。
摘 要:目的研究保留回盲部的腹腔镜右半结肠癌根治术(LISH)对右半结肠癌患者的治疗效果。方法将2021年1月至2023年12月期间60例右半结肠癌患者作为研究对象。采用随机数字表法分为观察组(n=30)和对照组(n=30),观察组接受LISH,对照组接受传统腹腔镜右半结肠根治术(LRH)。运用SPSS 27.0软件分析数据,围手术期指标等计量资料用(±s)表示,行独立样本t检验。术后并发症发生率以率表示,计数资料行χ^(2)检验。手术前后生活质量评分以(±s)表示,采用重复测量方差分析对比。P<0.05为差异有统计学意义。结果两组患者手术时间、术中出血量、住院时间相比,差异无统计学意义(P>0.05);观察组患者排便、进食、排气时间短于对照组(P<0.05)。观察组患者术后并发症发生率低于对照组(10.0%vs.33.3%,P<0.05);时间与方法在SF-36生活质量评分上不存在交互作用(P>0.05);时间、方法在SF-36生活质量评分上主效应显著(P<0.05);术后3、6、12个月两组患者SF-36生活质量评分均呈现逐步上升趋势,观察组患者术后3、6、12个月评分高于对照组(P<0.05)。结论针对右半结肠癌患者,实施LISH确保患者肿瘤根治效果的前提,能够有效缩减患者术后排便、进食及排气所需时间,显著降低并发症发生率,并改善患者术后远期生活质量。Objective To investigate the therapeutic effect of laparoscopic radical resection of right hemicolonic carcinoma(LISH)with ileocecal area preserved in patients with right hemicolonic carcinoma.Methods Sixty patients with right half colon cancer between January 2021 and December 2023 were studied.They were divided into observation group(n=30)and control group(n=30)by random number table method.The observation group received LISH,and the control group received traditional laparoscopic radical right hemicolectomy(LRH).SPSS 27.0 software was used to analyze the data.Measurement data such as perioperative indicators were represented by(±s)and independent sample t test was performed.The incidence of postoperative complications was expressed as rate,and the counting data were tested byχ^(2).The quality of life score before and after surgery was expressed as(x±s),and repeated measure ANOVA was used for comparison.P<0.05 was considered statistically significant.Results There was no significant difference in operation time,intraoperative blood loss and hospital stay between the two groups(P>0.05).The time of defecation,eating and exhaust in observation group was shorter than that in control group(P<0.05).The incidence of postoperative complications in observation group was lower than that in control group(10.0%vs.33.3%,P<0.05).There was no interaction between time and method on SF-36 quality of life score(P>0.05).The main effect of time and method on SF-36 quality of life score was significant(P<0.05).The SF-36 quality of life scores of both groups showed a gradually increasing trend at 3,6 and 12 months after surgery,and the scores of patients in the observation group were higher than those in the control group at 3,6 and 12 months after surgery(P<0.05).Conclusion For patients with right colon cancer,the implementation of LISH to ensure the effect of radical tumor treatment can effectively reduce the time required for postoperative defecation,eating and exhaust,significantly reduce the incidence of complications,and im
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