瘢痕疙瘩术后的辅助放疗  

Postoperative adjuvant radiotherapy for keloids

作　　者：凃贝霖 李伟[1] 许学文[1] Tu Beilin;Li Wei;Xu Xuewen(Department of Plastic and Burn Surgery,West China Hospital,Sichuan University,Chengdu 610041,China)

机构地区：[1]四川大学华西医院整形外科/烧伤科,成都610041

出　　处：《中华整形外科杂志》2025年第2期203-209,共7页Chinese Journal of Plastic Surgery

摘　　要：瘢痕疙瘩是一种皮肤对创伤或刺激过度反应形成的异常瘢痕组织,其主要病理特征是细胞外基质成分在真皮和皮下组织中过度沉积。目前最有效的治疗措施之一是手术切除联合术后放疗,但放疗时机、具体方式、剂量等尚无统一标准。该文通过回顾瘢痕疙瘩术后放疗的相关研究,对放疗方案、并发症等进行了归纳和总结,以期为瘢痕疙瘩的治疗与管理提供参考。Keloids are abnormal scar tissues that form as a result of the skin’s excessive reaction to trauma or stimulation.The primary pathological feature of keloids is the excessive deposition of extracellular matrix components in the dermis and subcutaneous tissue.Currently,surgical resection combined with postoperative radiotherapy is one of the most effective treatment strategies.However,there is no standardized protocol regarding the timing,specific methods,and dosage of radiotherapy.This paper reviewed existing research on radiotherapy following keloid surgery,summarizing the various radiotherapy regimens and associated complications to provide a reference for the treatment and management of keloids.

关 键 词：瘢痕疙瘩 外科手术 放疗 剂量分割 生物有效剂量 

分 类 号：R73[医药卫生—肿瘤]