妊娠合并子宫肌瘤孕妇发生先兆流产的影响因素调查分析  

Investigation and Analysis of Influencing Factors of Threatened Abortion in Pregnant Women with Uterine Fibroid

作　　者：王红亚[1] 孙萌[1] 吴芳芳 Wang Hongya;Sun Meng;Wu Fangfang(Department of Obstetrics and Gynecology,The Second Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan,450003,China)

机构地区：[1]郑州大学第二附属医院妇产科,河南郑州450003

出　　处：《黑龙江医学》2025年第5期600-603,共4页Heilongjiang Medical Journal

摘　　要：目的:分析妊娠合并子宫肌瘤孕妇先兆流产发生的有关影响因素。方法:回顾性分析2021年4月—2022年4月郑州大学第二附属医院收治的97例妊娠合并子宫肌瘤孕妇的临床资料,统计其先兆流产发生情况;另收集孕妇的年龄、文化程度等资料,探究其先兆流产发生的相关影响因素。结果:97例妊娠合并子宫肌瘤孕妇中,共有21例发生先兆流产,发生率为21.65%(21/97);单因素分析显示:文化程度、工作状态、吸烟史、饮酒史、妊娠期合并症、产次、子宫肌瘤部位与妊娠合并子宫肌瘤孕妇先兆流产的发生无关,差异均无统计学意义(χ^(2)=0.290、0.224、0.084、0.166、0.316、0.494、1.016,P>0.05);年龄、既往流产史、子宫肌瘤数目、子宫肌瘤直径、生殖道感染、黄体功能不全与妊娠合并子宫肌瘤孕妇先兆流产的发生有关,差异均有统计学意义(χ^(2)=11.701、15.478、9.570、10.871、20.853,P<0.05);logistic回归分析显示:年龄>35岁、既往有流产史、多个子宫肌瘤、子宫肌瘤直径大、有生殖道感染、黄体功能不全为妊娠合并子宫肌瘤孕妇先兆流产发生的独立危险因素(P<0.05)。结论:妊娠合并子宫肌瘤孕妇先兆流产发生风险较高,而其先兆流产发生的有关因素众多,如年龄>35岁、既往有流产史、多个子宫肌瘤、子宫肌瘤直径大、有生殖道感染、黄体功能不全等,对此临床需给予高度重视。Objective:To analyze the influencing factors of threatened abortion in pregnant women with uterine fibroid.Methods:The clinical data of 97 pregnant women with uterine fibroid in the Second Affiliated Hospital of Zhengzhou University from April 2021 to April 2022 were retrospectively analyzed,and the incidence of threatened abortion was counted.Information on the age of pregnant women and explore the relevant influencing factors of threatened miscarriage was collected.Results:Among 97 pregnant women with uterine fibroid,21 had threatened abortion(21.65%,21/97).Univariate analysis showed that education level,work status,smoking history,drinking history,pregnancy complications,birth times,uterine fibroid location were not related to the occurrence of threatened abortion in pregnant women with uterine fibroid,and the difference was not statistically significant(χ^(2)=0.290,0.224,0.084,0.166,0.316,0.494,1.016;P>0.05).Age>35 years old,previous abortion history,the number of Uterine fibroid,the diameter of uterine fibroid,genital tract infection,and luteal insufficiency were related to the occurrence of threatened abortion in pregnant women with uterine fibroid,and the difference was statistically significant(χ^(2)=11.701,15.478,9.570,10.871,20.853;P<0.05).Logistic regression analysis showed that age>35 years old,previous abortion history,multiple uterine fibroid,large uterine fibroid diameter,genital tract infection,luteal insufficiency were the independent risk factors for threatened abortion in pregnant women with uterine fibroid(P<0.05).Conclusion:Pregnant women with uterine fibroids in pregnancy have a higher risk of threatened miscarriage,and there are many related factors for the occurrence of threatened miscarriage,such as age>35 years old,previous history of miscarriage,multiple uterine fibroids,large diameter uterine fibroids,reproductive tract infections,and luteal dysfunction.Therefore,high attention should be paid to this clinical practice.

关 键 词：妊娠 子宫肌瘤 先兆流产 影响因素 黄体功能不全 生殖道感染 

分 类 号：R737.33[医药卫生—肿瘤]