A mechanistic study of radiotherapy on intratumoral NK cell infiltration augmentation by regulating the EZH2/CXCL10 pathway in hepatocellular carcinoma cells  

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作  者:ZHAO Xiaofang 赵晓芳(PLA Med Coll,Bejjing 100039)

机构地区:[1]PLA Med Coll,Bejjing 100039

出  处:《China Medical Abstracts(Internal Medicine)》2024年第4期223-223,共1页中国医学文摘(内科学分册英文版)

摘  要:Objective To investigate the effect and associated mechanism of tumor tissue-infiltrating NK cells after receiving radiotherapy for hepatoellular carcinoma(HCC).Methods A HCC tumor-bearing mouse model was constructed using human hepatoellular carcinoma cell line(SK-Hep-1)and divided into four groups:control,radiotherapy,NK cell clearance,and NK clearance combined with radiotherapy.

关 键 词:CXCL10 EZH2 carcinoma 

分 类 号:R73[医药卫生—肿瘤]

 

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