2018—2023年安庆市农村肺癌高危人群筛查结果分析  

Analysis of screening results of high-risk population for lungcancer in Anqing rural area from 2018 to 2023

作　　者：王莹莹[1] 江叶倩 李明珠 余艳[1] 李乾兵 WANG Yingying;JIANG Yeqian;LI Mingzhu;YU Yan;LI Qianbing(Department of Respiratory and Critical Care Medicine,Anqing First People's Hospital of Anhui Medical University,Anqing,Anhui 246000,China)

机构地区：[1]安徽医科大学附属安庆第一人民医院呼吸与危重症医学科,安徽安庆246000

出　　处：《中国临床研究》2025年第3期356-360,共5页Chinese Journal of Clinical Research

基　　金：安徽省省级临床重点专科建设项目(皖卫函[2023]320号);安庆市医疗卫生重点学科建设项目(宜卫宣教[2022]71号);2023年安庆市中央财政重大传染病防控项目(宜财社[2023]591号)。

摘　　要：目的 分析中国农村肺癌早诊早治项目2018—2023年安庆点高危人群筛查结果。方法 于2018—2023年筛查安庆市部分地区50~74岁高危人群,对其行低剂量螺旋CT(LDCT)扫描,统计阳性病变检出率并分析其相关影响因素。结果 共有2 041例高危个体入组,LDCT检出阳性结节356例(17.44%),110例提示疑似肺癌(5.39%),随访后确诊30例(1.47%),30例中,早期肺癌19例(63.33%),26例进入临床治疗程序(86.67%)。70~74岁、文化程度小学及以下、新鲜蔬菜瓜果摄入次数≤1次/d、有吸烟史、有特殊职业暴露史、有慢性呼吸道疾病史和肿瘤家族史人群肺内阳性结节和疑似肺癌检出率高(P<0.05)。Logistic回归分析结果显示,年龄、文化程度、吸烟史、特殊职业暴露史、慢性呼吸道疾病史、肿瘤家族史及新鲜蔬菜瓜果摄入是阳性结节和疑似肺癌发生的独立影响因素(P<0.01)。结论 对农村肺癌高危人群针对性筛查,有利于及时发现肺部阳性病变,提高肺癌早诊率和治疗率。Objective To analyze the screening results of high-risk groups in Anqing of the early diagnosis and treatment project for lung cancer in rural China from 2018 to 2023.Methods From 2018 to 2023,high-risk individuals aged 50 to 74 years in certain areas of Anqing City were screened using low-dose spiral CT(LDCT).The detection rates of positive lesions were counted and the related influencing factors were analyzed.Results A total of 2041 high-risk individuals were enrolled,356 cases(17.44%)had positive nodules;110 cases(5.39%)were suspected of lung cancer;after follow-up,30 cases(1.47%)were confirmed,including 19 cases of early-stage lung cancer(63.33%),and 26 cases entered clinical treatment programs(86.67%).The detection rates of positive pulmonary nodules and suspected lung cancers were higher in the individuals aged 70-74,with an education level of elementary school or below,consuming fresh vegetables and fruits≤1 time/d,having a history of smoking,special occupational exposure,chronic respiratory diseases,or a family history of cancer(P<0.05).Logistic regression analysis showed that age,education level,smoking history,special occupational exposure,history of chronic respiratory diseases,family history of cancer,and intake of fresh vegetables and fruits were independent influencing factors for the occurrence of positive nodules and suspected lung cancer(P<0.01).Conclusion Targeted screening of high-risk groups for lung cancer in rural areas is beneficial for the timely detection of positive pulmonary lesions,improving the early diagnosis and treatment rates of lung cancer.

关 键 词：肺癌 低剂量螺旋CT 肺结节 筛查 农村地区 

分 类 号：R734.2[医药卫生—肿瘤]