非小细胞肺癌侵犯胸膜或胸壁的影像诊断研究进展  

Chinese Expert Consensus on Assessment and Clinical Application of Tertiary Lymphoid Structure for Non-small Cell Lung Cancer(2025 Version)

作　　者：中国抗癌协会肿瘤病理专业委员会肺癌协作组 中国临床肿瘤学会非小细胞肺癌专业委员会 林冬梅 周彩存 李媛 沈波[8] Lung Cancer Collaboration Group of Tumor Pathology Committee of Chinese Anti-Cancer Association;Expert Committee on Non-small Cell Lung Cancer of Chinese Society of Clinical Oncology;Dongmei LIN;Caicun ZHOU;Yuan LI;Bo SHEN

机构地区：[1]不详 [2]北京大学肿瘤医院 [3]暨北京市肿瘤防治研究所病理科 [4]恶性肿瘤发病机制及转化研究教育部重点实验室 [5]上海市东方医院肿瘤科 [6]复旦大学附属肿瘤医院病理科 [7]复旦大学上海医学院肿瘤学系 [8]江苏省肿瘤医院/南京医科大学附属肿瘤医院内科

出　　处：《中国肺癌杂志》2025年第2期95-104,共10页Chinese Journal of Lung Cancer

基　　金：天津市医学重点学科(专科)建设项目(No.TJYXZDXK-009A)资助。

摘　　要：分期的准确诊断是非小细胞肺癌(non-small cell lung cancer, NSCLC)治疗和预后的基础,其中肿瘤是否累及胸膜或胸壁是评估周围型肺癌分期的重要环节。计算机断层扫描(computed tomography, CT)、磁共振成像(magnetic resonance imaging, MRI)、超声(ultrasound, US)和正电子发射断层扫描(positron emission tomography,PET)等影像技术广泛地应用于判断NSCLC是否有胸膜侵犯,并且已经有越来越多评估NSCLC是否侵犯胸膜及侵犯程度的研究,本文就胸膜受侵的分期和影像诊断标准作一综述,以期为同行对侵犯胸膜或胸壁的精准诊断提供参考。The tertiary lymphoid structure(TLS)plays a crucial role in the tumor microenvironment,influenc-ing tumor development and progression.As an emerging biomarker for predicting the prognosis and treatment response in cancer patients,TLS has received increasing attention.However,there is currently a lack of standardized evaluation criteria for TLS,and significant differences exist in TLS across different tumor tissues.This poses challenges for the clinical application of this biomarker in translation.To meet the clinical diagnosis and treatment needs of non-small cell lung cancer(NSCLC),this consensus focuses on the definition,clinical significance,testing components,and assessment methods of TLS in NSCLC.Combining relevant research and Chinese clinical practice,it provides standardized and normalized suggestions for the clinical assessment and application of TLS,so as to improve the understanding of TLS among clinicians and pathologists,and provide a reference basis for the clinical application of the detection of TLS in NSCLC.

关 键 词：肺肿瘤 胸膜 影像诊断 TNM分期 

分 类 号：R73[医药卫生—肿瘤]