肠腔内生性卵巢外腹膜浆液性乳头状腺癌1例并文献复习  

Intraluminal primary extra-ovarian peritoneal serous papillary carcinoma:A case report and literature review

作　　者：李忠标 赵习浩 杜敏[2] 王江 于跃 张佃良 Li Zhongbiao;Zhao Xihao;Du Min;Wang Jiang;Yu Yue;Zhang Dianliang(Qingdao Medical College,Qingdao University,Qingdao 266073,China;Department of Gastrointestinal Surgery,Qingdao Municipal Hospital,Qingdao 266011,China)

机构地区：[1]青岛大学青岛医学院,山东青岛266073 [2]青岛市市立医院胃肠外科,山东青岛266011

出　　处：《临床荟萃》2025年第3期257-261,共5页Clinical Focus

基　　金：国家自然科学基金面上项目Arpin和CPTP对重症急性胰腺炎肠上皮屏障的影响及分子机制(81470890)。

摘　　要：目的通过分析1例罕见生长类型的卵巢外腹膜浆液型乳头状癌(extra-ovarian peritoneal serous papillary carcinoma,EPSPC)病例,探讨这一疾病的临床、病理学特征及诊疗思路。方法回顾分析EPSPC患者1例并复习相关文献。结果患者中年女性,因排便习惯改变伴下腹部隐痛不适2个月就诊,肠镜示直肠巨大隆起性肿物,盆腔核磁示直肠囊样占位,剖腹探查见肿瘤累及直肠左前壁深达黏膜层,送检囊壁提示恶性,排除卵巢及子宫来源,遂行腹腔镜下直肠癌根治术,结合病理诊断为EPSPC。结论EPSPC临床误诊率高,尤其肠腔内生性EPSPC难与肠道原发腺癌鉴别,需依据临床及病理学特点来诊断。与同类型的卵巢癌相比EPSPC预后较差,手术联合化疗为主要治疗手段。Objective To examine a rare case of extra-ovarian peritoneal serous papillary carcinoma(EPSPC)with an atypical growth pattern and to evaluate its clinical and pathological features and diagnostic approach.Methods A middle-aged female patient with EPSPC was retrospectively analyzed,and relevant literature was reviewed.Results The patient presented with abdominal pain and altered bowel habits for two months.Colonoscopy and magnetic resonance imaging(MRI)revealed a large rectal mass and a rectal cystic lesion,respectively.Exploratory laparotomy showed tumor involvement of the rectal left anterior wall mucosa,and the cystic wall suggested malignancy.Histopathology excluded ovarian and uterine origins.Laparoscopic radical resection of rectal cancer was performed,and EPSPC was diagnosed.Conclusion EPSPC has a high clinical misdiagnosis rate,especially intraluminal EPSPC,which mimics primary intestinal adenocarcinoma.Diagnosis relies on clinical and pathological features.Compared to ovarian serous carcinoma,EPSPC has a poorer prognosis,with surgery and chemotherapy as the main treatment options.

关 键 词：腹膜肿瘤 腹膜浆液性乳头状癌 鉴别诊断 病例报道 

分 类 号：R735.5[医药卫生—肿瘤]