人体成分分析在放疗中的应用进展与临床意义  

Advances and clinical significance of body composition analysis in radiation therapy

作　　者：严玲[1] 廖正凯[2] Yan Ling;Liao Zhengkai(Department of Cardiology,Renmin Hospital of Wuhan University/Hubei Key Laboratory of Metabolic and Chronic Diseases,Wuhan 430060,Hubei,China;Department of Radiation and Medical Oncology,Hubei Key Laboratory of Tumor Biological Behaviors,Hubei Cancer Clinical Study Center,Wuhan 430071,Hubei,China)

机构地区：[1]武汉大学人民医院心血管内科,代谢与相关慢病湖北省重点实验室,湖北武汉430060 [2]武汉大学中南医院肺部肿瘤放化疗科,肿瘤生物学行为湖北省重点实验室,湖北省肿瘤医学临床研究中心,湖北武汉430071

出　　处：《肿瘤代谢与营养电子杂志》2025年第1期25-29,共5页Electronic Journal of Metabolism and Nutrition of Cancer

基　　金：国家自然科学基金面上项目(81870299)。

摘　　要：随着医学技术的进步,人体成分分析(BCA)作为一种非侵入性、易于操作的评估工具,在放疗领域显示出越来越重要的作用。BCA通过精确量化患者的肌肉量、脂肪量和水分等关键指标,为放疗患者的营养状态评估提供了新维度。这些指标不仅反映了患者的代谢状态,还能预测治疗疗效和潜在的不良反应风险,为个性化放疗计划的制定提供了科学依据。当前,在放疗患者中应用BCA,不仅能优化治疗方案、提高治疗效果,还能降低患者毒副反应,改善其生活质量。本文综述了近年来BCA在放疗患者中的研究进展,探讨了放疗对患者身体成分的影响,以及这些变化与治疗效果和患者预后的关系。同时,对当前常用的BCA方法进行了评估,包括其优势和局限性。本文旨在推动BCA在放疗临床实践中的常规应用,通过精准的身体成分分析为患者提供更为个性化和高效的治疗方案。此外,本文还展望了BCA技术的未来发展方向,以及如何通过技术创新满足临床需求,进一步提升放疗的科学性和有效性。With the advancement of medical technology,body composition analysis(BCA).as a non-invasive and user-friendly assessment tool,has played an increasingly significant role in the field of radiation therapy.BCA provides a new dimension for evaluating the nutritional status of radiation therapy patients by precisely quantifying key indicators such as muscle mass,fat mass,and body water content.These indicators not only reflect the metabolic status of patients but also predict treatment outcomes and potential risks of adverse reactions,providing a scientific basis for the formulation of personalized radiation therapy plans.Currently,the application of BCA in the management of radiation therapy patients has demonstrated remarkable potential,optimizing treatment regimens,improving therapeutic efficacy,and reducing toxic side effects,thereby enhancing patients'quality of life.This review summarizes recent research progress on the application of BCA in radiation therapy patients,explores the effects of radiation therapy on patients'body composition,and the relationship between these changes and treatment outcomes and patient prognosis.Meanwhile,it evaluates currently used BCA methods,including their advantages and limitations.We aim to promote the routine clinical application of BCA in radiation therapy,providing patients with more personalized and effective treatment plans through precise body composition analysis.Furthermore,this article looks into the future development directions of BCA technology and how technological innovations can meet clinical needs,further enhancing the scientificity and effectiveness of radiation therapy.

关 键 词：人体成分分析 放疗 营养状态评估 肿瘤 个性化治疗 瘦体组织 生物电阻抗 相位角 

分 类 号：R73[医药卫生—肿瘤]