Global burden of soil-transmitted helminth infections,1990-2021  

作　　者：Jin Chen Yanfeng Gong Qin Chen Shizhu Li Yibiao Zhou 

机构地区：[1]Fudan University School of Public Health,Fudan University Center for Tropical Disease Research,Shanghai 200032,China [2]National Institute of Parasitic Diseases,Chinese Center for Disease Control and Prevention,Chinese Center for Tropical Diseases Research,National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases,Key Laboratory on Parasite and Vector Biology,Ministry of Health,WHO Collaborating Centre for Tropical Diseases,National Center for International Research on Tropical Diseases,Ministry of Science and Technology,Shanghai 200025,China [3]School of Global Health,Chinese Center for Tropical Diseases Research,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China.

出　　处：《Infectious Diseases of Poverty》2024年第5期68-77,共10页贫困所致传染病(英文)

基　　金：supported by the National Parasite Resource Center(Project No.2019-194-30);this study is also supported by Key Project of Preliminary Research for the"15th Five-Year"Disease Control and Prevention Plan of National Disease Control and Prevention Administration,and International Joint Laboratory on Tropical Diseases Control in Greater Mekong Subregion(No.21410750200)from Shanghai Municipality Government.

摘　　要：Background Soil-transmitted helminth(STH)infections can cause a significant disease burden.It is estimated that 1.5 billion people worldwide are infected with STHs,primarily in tropical and subtropical regions.This study aimed to assess the distribution of the global burden and trend of STH infections from 1990 to 2021.Methods We retrieved data from the Global Burden of Diseases,Injuries,and Risk Factors Study 2021 on the age-standardized rates(ASRs)of prevalence and disability-adjusted life-years(DALYs)of STH infections for all age groups in 204 countries and territories from 1990 to 2021.The ASRs of prevalence and DALYs by age,gender,and sociodemographic index(SDI)were calculated to quantify the spatial distribution and temporal trend.Spearman correlation analysis was used to examine the relationship between ASR and SDI.Results In 2021,there were an estimated 642.72 million cases and 1.38 million DALYs caused by STH infections worldwide.The age-standardized prevalence rate(ASPR)of STH infections was 8429.89[95%uncertainty interval(UI):7697.23,9362.18]per 100,000 population globally.The ASPR of STH infections varied across 21 geographic regions in 2021,being mainly prevalent in most African and Latin American locations.The prevalence was higher in the groups of 5-19 years,especially the group of 5-9 years with the ASPR of 16,263(95%UI:14,877.06,18,003.49)and ASR of DALYs of 40.69(95%UI:25.98,60.91)per 100,000.The ASPR of STH infections showed an obvious decreasing trend worldwide(estimated annual percent change=-4.03,95%confidence interval:-4.13,-3.93)with variations in different species infections during the study years.At the regional level,the ASR of STH infections prevalence(r=-0.8807,P<0.0001)and DALYs(r=-0.9069,P<0.0001)were negatively correlated with SDI.Conclusions STH infections remain a public health problem in 2021,particularly in regions such as the middle parts of Africa and Americas,and in the 5-19 age populations.The reduction in the rate of prevalence and the loss of DALYs are negatively correlat

关 键 词：Soil-transmitted helminth infections Disease burden Age GENDER Geographical distribution Sociodemographic index ELIMINATION 

分 类 号：G63[文化科学—教育学]