Integrative analysis of the metabolomes and transcriptomes of Ebola virus-infected cells:Uncovering pathways related to hepatic apoptosis  

作　　者：Chenchen Liu Zengguo Cao Cheng Peng Fangxu Li Zixi Chen Xinghai Zhang Xiaoying Jia Jinge Zhou Wenting Mao Entao Li Gengfu Xiao Sandra Chiu 

机构地区：[1]Key Laboratory of Special Pathogens and Biosafety,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan,Hubei 430071,China [2]University of Chinese Academy of Sciences,Bejing 100190,China [3]National Biosafety Laboratory,Chinese Academy of Sciences,Wuhan,Hubei 430020,China [4]Shenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science,Shenzhen Engineering Laboratory for Marine Algal Biotechnology,Guangdong Provincial Key Laboratory for Plant Epigenetics,College of Life Sciences and Oceanography,Shenzhen University,Shenzhen,Guangdong 518060,China [5]Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230026,China [6]Department of Laboratory Medicine,The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230026,China [7]Key Laboratory of Anhui Province for Emerging and Reemerging Infectious Diseases,Hefei,Anhui 230026,China [8]Wuhan institute virology,Chinese Academy of Sciences,Wuhan,Hubei 430071,China

出　　处：《Genes & Diseases》2025年第2期129-132,共4页基因与疾病(英文)

基　　金：supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (No.XDB0490000);the National Natural Science Foundation of China (No.82202521);the China Postdoctoral Science Foundation Funded Project (No.202122M723345).

摘　　要：Ebola virus(EBOV)belongs to the Filoviridae family within the genus Ebolavirus and is responsible for the highly lethal hemorrhagic disease known as Ebola virus disease(EVD).The clinical manifestations of EVD include hemorrhagic fever,organ failure,and immune dysfunction.

关 键 词：EBOLA HEMORRHAGIC INFECTED 

分 类 号：R51[医药卫生—内科学]