EBOLA

作品数：142被引量：164H指数：7
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Integrative analysis of the metabolomes and transcriptomes of Ebola virus-infected cells:Uncovering pathways related to hepatic apoptosis
《Genes & Diseases》2025年第2期129-132,共4页Chenchen Liu Zengguo Cao Cheng Peng Fangxu Li Zixi Chen Xinghai Zhang Xiaoying Jia Jinge Zhou Wenting Mao Entao Li Gengfu Xiao Sandra Chiu 
supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (No.XDB0490000);the National Natural Science Foundation of China (No.82202521);the China Postdoctoral Science Foundation Funded Project (No.202122M723345).
Ebola virus(EBOV)belongs to the Filoviridae family within the genus Ebolavirus and is responsible for the highly lethal hemorrhagic disease known as Ebola virus disease(EVD).The clinical manifestations of EVD include ...
关键词：EBOLA HEMORRHAGIC INFECTED 
Barriers and facilitators to healthcare facility utilization by non-Ebola patients during the 2018-2020 Ebola outbreak in the Democratic Republic of Congo
《Global Health Research and Policy》2024年第1期71-81,共11页Gabriel Kalombe Kyomba Michael Robert Law Karen Ann Grépin Serge Manitu Mayaka Thérèse Nyangi‑Mondo Mambu Branly Kilola Mbunga Celestin Hategeka Mala Ali Mapatano Joël Nkiama‑Numbi Konde Dosithée Ngo‑Bebe Pélagie Diambalula Babakazo Eric Musalu Mafuta Guillaume Mbela Kiyombo 
No direct funding was provided for this paper.However,to collect data,the principal investigator jumped on the opportunity to be in the field with a larger research project funded by the Rapid Research Fund for Ebola which was supported by the International Development Research Centre(IDRC),Grant number,108966-002,KAG and SMM.
Background An Ebola Virus Disease(EVD)outbreak occurred in North Kivu between 2018 and 2020.This eastern province of the Democratic Republic of Congo was also grappling with insecurity caused by several armed groups.T...
关键词：Healthcare facility Health service utilization Ebola Virus Disease Preparedness and response Free care policy Personal protective equipment North Kivu Democratic Republic of Congo 
Ebola virus disease model with a nonlinear incidence rate and density-dependent treatment
《Infectious Disease Modelling》2024年第3期775-804,共30页Jacques NdéKengne Calvin Tadmon 
C.Tadmon acknowledges good working conditions at the institute of Mathematics,University of Mainz,where this paper has been finalised during a research stay supported by the Alexander von Humboldt Foundation.
This paper studies an Ebola epidemic model with an exponential nonlinear incidence function that considers the efficacy and the behaviour change.The current model also incorporates a new density-dependent treatment th...
关键词：Ebola epidemic models STABILITY BIFURCATION Density-dependent treatment Sensitivity analysis Fractional differential equations Caputo fractional derivative Grünwald-letnikov nonstandard finite difference scheme 
Current updates on the epidemiology,pathogenesis and development of small molecule therapeutics for the treatment of Ebola virus infections
《Asian Pacific Journal of Tropical Medicine》2024年第7期285-298,I0001-I0007,共21页Shah Alam Khan Neelima Shrivastava MdJawaid Akhtar Aftab Ahmad Asif Husain 
Ebola virus disease(EVD)is a rare,highly contagious and a deadly disease with a variable fatality rate ranging from 30%to 90%.Over the past two decades,Ebola pandemic has severely affected the sub-Sahara region includ...
关键词：EBOLA EPIDEMIC Vaccine Ebola virus diseas 
A causal multiomics study discriminates the early immune features of Ad5-vectored Ebola vaccine recipients
《The Innovation》2024年第3期77-87,共11页Zhe Zhang Wenjing Yang Zhengshan Chen Haoang Chi Shipo Wu Wanru Zheng Ruochun Jin Busen Wang Yudong Wang Nan Huo Jinlong Zhang Xiaohong Song Liyang Xu Jun Zhang Lihua Hou Wei Chen 
National Natural Science Foundation of China 31900671.
The vaccine-induced innate immune response is essential for the generation of an antibody response.To date,how Ad5-vectored vaccines are influenced by preexisting anti-Ad5 antibodies during activation of the early imm...
关键词：VACCINE immunity alterations 
具有媒体播报效应的埃博拉传染病模型的动力学分析被引量：1
《华中师范大学学报（自然科学版）》2024年第3期298-303,共6页李佳慧 王晓静 郭松柏 梁宇 郭德玉 
国家自然科学基金项目(11901027);北京市教育委员会科研计划项目(SZ202110016008);北京建筑大学2022年度研究生创新项目(PG2022142).
该文依据埃博拉的传播机制,构建一类具有媒体播报效应及有限医疗资源环境下的SIRDM传染病模型,计算模型的控制再生数,证明了无病平衡点的存在性、全局稳定性以及地方病平衡点的存在唯一性.然后对控制再生数进行敏感性分析,最后进行数值...
关键词：埃博拉(Ebola) 控制再生数 稳定性 敏感性分析 数值模拟 
Re-emergence of Ebola virus disease in Uganda:Should Southeast Asia countries be worried?
《Journal of Safety Science and Resilience》2023年第3期262-264,共3页Haruna Muhammad Daiyab Farouq Muhammad Dayyab 
An outbreak of Ebola virus disease(EVD)(Sudan virus)was first reported in the Republic of Uganda on September 20,2022.As of November 17,2022,151 confirmed cases have been reported,including 55 deaths(with a case fatal...
关键词：EBOLA Uganda Southeast Asia OUTBREAK 
Sustainable Laboratory Capacity Building in Sierra Leone:From Ebola to COVID-19
《China CDC weekly》2023年第28期632-636,共5页Lili Wang Alie Brima Tia Bing Xu Xiaopeng Qi Doris Harding 
The onset of the Ebola outbreak in 2014 originated in Guinea and proceeded to swiftly reach Sierra Leone and Liberia(1).Unfortunately,these nations were critically deficient in their capacity for pathogenic testing an...
关键词：EBOLA PREVENTION thereby 
Inhibiting the transcription and replication of Ebola viruses by disrupting the nucleoprotein and VP30 protein interaction with small molecules
《Acta Pharmacologica Sinica》2023年第7期1487-1499,共13页Yan-hong Ma Xu Hong Fang Wu Xin-feng Xu Rui Li Jin Zhong Yao-qi Zhou Shu-wen Liu Jian Zhan Wei Xu 
the National Natural Science Foundation of China(82173865,82130101);Foundation of Advanced Customer Cultivation Project of Wuhan National Biosafety Laboratory,Chinese Academy of Sciences,Shenzhen Bay Laboratory Open Fund(SZBL2021080601010);Major Program of Shenzhen Bay Laboratory(S201101001).
Ebola virus(EBOV)causes hemorrhagic fever in humans with high morbidity and fatality.Although over 45 years have passed since the first EBOV outbreak,small molecule drugs are not yet available.Ebola viral protein VP30...
关键词：EBOLA VP30 MINIGENOME high-throughput screening drug synergy 
Lessons for Epidemic Emergency Policy: A Scoping Review of Ebola and COVID-19 Pandemics in Africa
《Health》2023年第7期814-837,共24页Sam Agatre Okuonzi 
Ebola Virus Disease (EVD) outbreaks in Central and West Africa 2013-2020 were the deadliest, most intense and most widely spread. On top of this, the novel Corona Virus Disease 2019 (COVID-19) has given us all a new e...
关键词：COVID-19 EBOLA Emergency Response Policy Health Security Global Cooperation 
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