Locoregional treatments of metastatic internal mammary node following neoadjuvant chemotherapy  

作　　者：Jinhui Zhang Huajie Guan Cailu Song Lingrui Liu Hailin Tang Jin Wang 

机构地区：[1]Department of Breast Oncology,State Key Laboratory of Oncology in South China,Guangdong Provincial Clinical Research Center for Cancer,Sun Yat-Sen University Cancer Center,Guangzhou,Guangdong 510060,China

出　　处：《Chinese Medical Journal》2025年第3期358-360,共3页中华医学杂志(英文版)

基　　金：National Natural Science Foundation of China(No.82273399);Natural Science Foundation of Guangdong Province(No.2022A1515012229);National Natural Science Foundation of China(No.82372742)

摘　　要：To the Editor:Neoadjuvant chemotherapy(NAC)significantly improves the prognosis for patients with breast cancer with internal mammary lymph node(IMN)involvement,[1]but the locoregional treatment of IMNs including IMN dissection(IMND)and IMN boost irradiation(IMNB)has long been debated,[2]owing to the difficulty in surgical approaches and cardiopulmonary side effects caused by high-dose radiation.[3]To date,the surgical dissection of IMNs is rarely performed;thus,the data regarding survival outcome of IMND is quite limited.In terms of radiotherapy(RT),there is marked discrepancy in radiation dose to IMNs in patients with metastatic IMN following NAC.[4]In this study,we report our institutional experience in the locoregional treatment of metastatic IMN and its impact on prognosis in patients who have undergone NAC.

关 键 词：surgical approaches locoregional treatment breast cancer imn boost irradiation imnb cardiopulmonary side effects metastatic internal mammary node internal mammary lymph node imn involvement surgical dissection 

分 类 号：R737.9[医药卫生—肿瘤]