胆囊癌辅助诊断研究进展  

Research progress in adjuvant diagnosis of gallbladder cancer

作　　者：郑大雯 王健东[1] Zheng Dawen;Wang Jiandong(Department of General Surgery,Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200092,China)

机构地区：[1]上海交通大学医学院附属新华医院普通外科,200092

出　　处：《中华肝脏外科手术学电子杂志》2024年第6期769-773,共5页Chinese Journal of Hepatic Surgery(Electronic Edition)

基　　金：上海市2021年度“科技创新行动计划”医学创新研究专项面上项目(21Y11912400)

摘　　要：胆囊癌恶性程度高,预后差。由于其早期无典型临床症状和解剖结构的特点,大部分胆囊癌患者确诊时肿瘤至中晚期,无根治性手术机会。目前临床上仍缺乏特异性的胆囊癌辅助诊断方法。本综述旨在简要概述当前胆囊癌研究领域中所采用的辅助诊断方法及包括液体活检在内的相关研究进展,以期为未来胆囊癌的精准诊断与治疗提供有益的参考。Gallbladder cancer has high-degree malignancy and poor prognosis.Due to atypical clinical symptoms and anatomical structures during the early stage,most patients are diagnosed with moderate and advanced gallbladder cancer upon admission,losing the opportunity for radical resection.At present,specific adjuvant diagnostic method is still lacking for gallbladder cancer in clinical practice.In this article,research progress in adjuvant diagnostic methods for gallbladder cancer including liquid biopsy was briefly reviewed,aiming to provide useful reference for accurate diagnosis and treatment of gallbladder cancer in the future.

关 键 词：胆囊癌 辅助诊断 液体活检 循环肿瘤细胞 胆汁脱落细胞检查 CA19-9 超声造影检查 CT MRI 

分 类 号：R735.8[医药卫生—肿瘤]