神经导航联合术中神经电生理监测在脑干胶质瘤手术切除中的应用  

Application of neuronavigation combined with intraoperative neurophysiological monitoring in surgical resection of brainstem glioma

作　　者：王莹莹 Yingying Wang(Department of Neurosurgery,the 910th Hospital of Quanzhou Joint Logistics Support Force,Quanzhou 362000,China)

机构地区：[1]泉州市联勤保障部队第九一〇医院神经外科,福建泉州362000

出　　处：《中华神经创伤外科电子杂志》2024年第5期293-298,共6页Chinese Journal Of Neurotraumatic Surgery:Electronic Edition

摘　　要：目的探究神经导航联合术中神经电生理监测(IONM)在脑干胶质瘤手术切除中的应用价值。方法回顾性分析泉州市联勤保障部队第九一〇医院神经外科自2018年8月至2020年4月收治的107脑干胶质瘤患者的临床资料。根据不同手术方法将患者分为观察组(神经导航联合IONM技术切除肿瘤,55例)和对照组(传统颅脑显微技术辅助切除肿瘤,52例)。比较2组患者的临床疗效、围术期指标、神经功能、日常生活活动能力、生存情况及术后并发症。结果观察组患者的肿瘤切除程度及手术治疗效果均优于对照组,手术时长及术后住院时长均短于对照组,差异有统计学意义(P<0.05)。观察组患者术后6个月的卡氏功能状态评分及功能独立性评定量表评分均高于对照组,差异有统计学意义(P<0.05)。随访2年,观察组患者的平均生存期为(26.77±7.69)个月,无进展生存期为(23.21±6.45)个月,对照组患者的平均生存期为(21.00±7.15)个月,无进展生存期为(18.75±5.58)个月,观察组患者的生存情况优于对照组,差异有统计学意义(P<0.05)。观察组患者的术后并发症总发生率低于对照组,差异有统计学意义(P<0.05)。结论在脑干胶质瘤手术切除中应用神经导航联合IONM技术,可提高肿瘤切除程度,提高手术疗效及术后生存质量,明显改善患者神经功能及日常活动能力,降低手术并发症发生率。Objective To explore the application value of neuronavigation combined with intraoperative neurophysiological monitoring(IONM)in the surgical resection of brainstem glioma.Methods The case data of 107 patients with brainstem glioma treated in Neurosurgery Department of the 910th Hospital of Quanzhou Joint Logistics Support Force from August 2018 to April 2020 were retrospectively analyzed,and the patients were divided into observation group(neuronavigation combined with IONM for tumor resection,n=55)and control group(traditional craniocerebral microsurgery-assisted tumor resection,n=52)according to different surgical methods.The clinical efficacy,perioperative indicators,neurological function,activity of daily living,survival quality and surgical complications were compared between two groups.Results The tumor resection degree and surgical treatment effect of the observation group were better than those of the control group,and the surgical duration and postoperative hospital stay were shorter than those of the control group,with statistical significance(P<0.05).The scores of Karnofsky functional status and functional independence measure of the observation group at 6 months after surgery were higher than those of the control group,and the difference was statistically significant(P<0.05).After a 2-year follow-up,the average survival period of the observation group was(26.77±7.69)months,and the progression free survival period was(23.21±6.45)months.The average survival period of the control group was(21.00±7.15)months,and the progression free survival period was(18.75±5.58)months.The survival of the observation group was better than that of the control group,and the difference was statistically significant(P<0.05).The total incidence of surgical complications in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The application of neuronavigation combined with IONM can enhance the degree of tumor resection,increase the surgical eff

关 键 词：脑干胶质瘤 神经导航 神经电生理监测 

分 类 号：R739.41[医药卫生—肿瘤]