International outbreak of acute pediatric hepatitis:Was acetaminophen the missing link?  

作　　者：Stephen A.Hoption Cann 

机构地区：[1]School of Population and Public Health,University of British Columbia,Vancouver,Canada

出　　处：《Pediatric Investigation》2024年第4期241-243,共3页儿科学研究(英文)

摘　　要：During the outbreak of acute pediatric hepatitis,two centers reported a threefold increase in cases.1 In their report,the hepatitis was preceded by an acute viral infection with a period of fasting.Patients ranged in age from 3 months to 5 years.One notable finding was that all patients had received acetaminophen therapeutically at least two days before onset.Despite receiving normal doses,the authors asserted that“the potential for this injury may have been augmented by ingestion of therapeutic doses of acetaminophen while patients were in a fasted state”.One might be surprised to learn that this was not a report from the well-known outbreak of acute childhood hepatitis that occurred in the winter and spring of 2021–2022,but an outbreak that was reported 30 years earlier.

关 键 词：ACETAMINOPHEN acute viral infection viral infection OUTBREAK FASTING acute pediatric hepatitis 

分 类 号：R725.7[医药卫生—儿科]