老年人睡眠时间与抑郁症状关联的剂量反应关系  

Dose-response relationship between sleep duration and depression in older adults

作　　者：朱琪 郝小吉 ZHU Qi;HAO Xiaoji(Department of Epidemiology and Health Statistics,School of Public Health,North Sichuan Medical College,Nanchong,Sichuan 637100,China;不详)

机构地区：[1]川北医学院公共卫生学院流行病学与卫生统计学教研室,四川南充637100 [2]浙江省疾病预防控制中心职业健康与辐射防护所

出　　处：《中国预防医学杂志》2025年第2期217-222,共6页Chinese Preventive Medicine

摘　　要：目的探讨睡眠时间与老年人抑郁症状关联强度的剂量-反应关系,为预防老年人抑郁提供依据。方法采用2020年中国家庭追踪(China Family Panel Studies,CFPS)调查数据。采用多因素logistic回归模型探讨睡眠时间与老年人抑郁症状的关联,采用限制性立方样条模型探讨睡眠时间的连续变化与抑郁症状的剂量-反应关系。结果纳入≥65岁老年人3112名,有抑郁症状786例,抑郁症状检出率25.26%。在调整了多种混杂因素后,与适宜总睡眠时间(>8~9 h)相比,总睡眠时间0~8、>9~10、>10 h的人群抑郁症状危险的OR值(95%CI)分别为1.48(1.17~1.87)、0.99(0.71~1.36)、1.60(1.15~2.23);与适宜夜间睡眠时间(>7~8 h)相比,夜间睡眠时间0~7、>8~9、>9 h的人群抑郁症状危险的OR值(95%CI)分别为1.36(1.11~1.68)、0.91(0.66~1.25)、1.51(1.08~2.10);与不午睡者相比,午睡时间0~<60、60~<90、≥90 min的人群抑郁症状危险的OR值(95%CI)分别为0.71(0.54~0.93)、0.67(0.54~0.84)、0.88(0.68~1.11)。限制性立方样条模型结果显示,总睡眠时间、夜间睡眠时间与午睡时间与抑郁症状均呈“U”型关联(P<0.001)。结论睡眠时间过长或过短与较高的抑郁症状危险相关,保持适宜睡眠时间可能是预防老年抑郁的有效途径。Objective To examine the dose-response relationship between sleep duration and the prevalence of depression symptoms in the elderly,providing evidence for the prevention of depression in this population.Methods Data from the 2020 China Family Panel Studies(CFPS)survey were utilized.A multivariate logistic regression model was used to explore the association between sleep duration and depression symptoms in older adults,while a restricted cubic spline model was used to explore the dose-response relationship of continuous variations in sleep duration with depression symptoms.Results A total of 3112 individuals aged 65 and older were included,with 786 exhibiting depression symptoms,resulting in a detection rate of 25.26%.After adjusting for confounding factors,the OR(95%CI)for depression symptoms with sleep duration of 0-8 h,>9-10 h,>10 h compared with the optimal sleep duration(>8-9 h)were 1.48(1.17,1.87),0.99(0.71,1.36),and 1.60(1.15,2.23),respectively.The OR(95%CI)of depression with a nighttime sleep duration of 0-7 h,>8-9 h,>9 h compared with the optimal sleep duration(>7-8 h)were 1.36(1.11,1.68),0.91(0.66-1.25)and 1.51(1.08-2.10),respectively.The OR(95%CI)of depression with nap duration of 0-<60 minutes,60-<90 minutes,and≥90 minutes compared with individuals who did not nap were 0.71(0.54-0.93),0.67(0.54-0.84)and 0.88(0.68-1.11),respectively.The restricted cubic spline model indicated a"U"-shaped association between total sleep duration,nighttime sleep duration,napping,and depression symptoms(P<0.001).Conclusions Both excessively long and short sleep durations are associated with a higher risk of depression symptoms.Maintaining an appropriate sleep duration may be an effective strategy for preventing depression in the elderly.

关 键 词：睡眠时间 抑郁症状 剂量-反应关系 老年人 

分 类 号：R181[医药卫生—流行病学]