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作 者:崔淞奎 张跃[1] CUI Songkui;ZHANG Yue(Department of Gastrointestinal Surgery,Xuzhou Cancer Hospital,Xuzhou 221005,China)
机构地区:[1]徐州市肿瘤医院胃肠外科,江苏徐州221005
出 处:《中国医学创新》2025年第8期47-50,共4页Medical Innovation of China
摘 要:目的:探究经鼻插入肠梗阻导管联合经自然腔道取标本手术(NOSES)治疗梗阻性结直肠癌(OCRC)的效果。方法:选择2021年1月—2024年1月在徐州市肿瘤医院治疗的64例OCRC患者,根据随机数字表法分为对照组及试验组,各32例。对照组行肠道支架联合腹腔镜手术治疗,试验组行经鼻插入肠梗阻导管联合NOSES治疗。比较两组手术情况、术后疗效、生活质量及并发症发生率。结果:试验组术前准备时间、手术时间均短于对照组,术中出血量少于对照组,差异均有统计学意义(P<0.05);两组置入成功率比较,差异无统计学意义(P>0.05)。试验组术后排气时间早于对组,住院时间短于对照组,症状缓解时间晚于对照组,差异均有统计学意义(P<0.05);两组症状缓解率比较,差异无统计学意义(P>0.05)。两组并发症发生率、生活质量评分比较,差异均无统计学意义(P>0.05)。结论:经鼻插入肠梗阻导管联合NOSES治疗OCRC效果显著,可改善临床症状,且安全有效,能促进预后康复,具有临床推广价值。Objective:To explore the efficacy of nasal insertion of intestinal obstruction catheters combined with natural orifice specimen extraction surgery(NOSES)in the treatment of obstructive colorectal cancer(OCRC).Method:A total of 64 OCRC patients treated in Xuzhou Cancer Hospital from January 2021 to January 2024 were selected and divided into control group and experimental group according to random number table method,with 32 cases in each group.The control group received intestinal stents combined with laparoscopic surgery,and the experimental group received nasal insertion of intestinal obstruction catheters combined with NOSES therapy.The operation status,postoperative efficacy,quality of life and complication rate of the two groups were compared.Result:The preoperative preparation time and operation time of experimental group were shorter than those of control group,and the intraoperative blood loss was less than that of control group,the differences were statistically significant(P<0.05).There was no significant difference in the success rate of implantation between the two groups(P>0.05).Postoperative exhaust time in experimental group was earlier than that in control group,hospital stay was shorter than that in control group,and symptom remission time was later than that in control group,the differences were statistically significant(P<0.05).There was no significant difference in symptom remission rate between the two groups(P>0.05).There were no significant differences in complication rate and quality of life score between the two groups(P>0.05).Conclusion:The combination of nasal insertion of intestinal obstruction catheters and NOSES in the treatment of OCRC has significant effects,can improve clinical symptoms,is safe and effective,can promote prognosis and recovery,and has clinical promotion value.
关 键 词:经鼻插入肠梗阻导管 经自然腔道取标本手术 梗阻性结直肠癌
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