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作 者:赵紫伟 彭静 梁燕 ZHAO Ziwei;PENG Jing;LIANG Yan(School of Health Care,Yunnan Open University,Kunming,Yunnan 650500,China;Department of Pharmacy,No.920 Hospital of the Chinese People’s Liberation Army Joint Logistics Support Force,Kunming,Yunnan 650000,China)
机构地区:[1]云南开放大学健康护理学院,云南昆明650500 [2]中国人民解放军联勤保障部队第九二〇医院药学部,云南昆明650000
出 处:《中国医药指南》2025年第9期56-58,共3页Guide of China Medicine
基 金:云南省高职院校大学生幽门螺杆菌感染检测及相关影响因素分析(课题编号:2024J0765)。
摘 要:幽门螺杆菌(Hp)感染是慢性胃炎、胃溃疡和胃癌的重要病因,常用治疗方法包括三联疗法和四联疗法,但耐药性问题日益严重。中医药在抑制Hp生长方面展现显著优势,通过调节体内环境和增强免疫力,有效提高了根除率。中药单体成分吡嗪类化合物、甘草次酸和黄芪甲苷等通过多种机制抑制Hp,且中西医结合疗法效果显著。Helicobacter pylori(Hp)infection is an important cause of chronic gastritis,gastric ulcer and gastric cancer.Commonly used treatments include triple therapy and quadruple therapy,but drug resistance is an increasingly serious problem.Traditional Chinese medicine has shown significant advantages in inhibiting the growth of Hp,effectively improving the eradication rate by regulating the internal environment and enhancing immunity.The monomer components of traditional Chinese medicine,pyrazine compounds,glycyrrhetinic acid,and astragaloside IV,inhibit H through various mechanisms,and the combined therapy of traditional Chinese and Western medicine has a significant effect.
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