角蛋白高值化利用研究进展  

Research Progress on High-value Utilization of Keratin

作　　者：王飞[1] 王会 郑朝中 莫潜渊 刘少娟 庄志凯 陈文坚 李建伟 WANG Fei;WANG Hui;ZHENG Chaozhong;MO Qianyuan;LIU Shaojuan;ZHUANG Zhikai;CHEN Wenjian;LI Jianwei(Agricultural Products Processing Research Institute,Chinese Academy of Tropical Agricultural Sciences,Zhanjiang 524001,China;Zhanjiang Ziking Fiderdown Production Co.,Ltd.,Zhanjiang 524000,China)

机构地区：[1]中国热带农业科学院农产品加工研究所,广东湛江524001 [2]湛江紫荆羽绒制品有限公司,广东湛江524000

出　　处：《生物化工》2025年第1期203-209,共7页Biological Chemical Engineering

基　　金：海南省自然科学基金(521MS0799);2023年省科技创新战略专项资金——制造业高新技术企业树标提质专题(2023A102)。

摘　　要：角蛋白是难降解的纤维蛋白,是自然界中三大最常见的聚合物之一,丰度仅次于甲壳素和纤维素。角质废料的生物水解是高值化利用的重要手段。生物法凭借其环境友好、低成本、高降解效率等优势成为最具潜力的角蛋白高值化利用方式。本文通过对角蛋白酶的种类、理化性质、异源表达及作用机制的系统梳理,详细介绍了其在饲料、生物肥料、食品、制革和医药美容等多个行业中的应用现状,为角蛋白酶降解机制研究和应用提供了新的思路。As the third most common polymer in nature,keratin is a fibrous protein difficult to degrade,second only in abundance to chitin and cellulose.The biohydrolysis of cutin waste is an important means of high value utilization.Biological methods become the most promising high-value utilization of keratin due to their advantages of environmental friendliness,low cost,and high degradation efficiency.This article systematically reviews the types,physicochemical properties,heterologous expression,and mechanism of action of keratinase,and provide its broad application status in multiple industries such as feed,biological fertilizers,food,leather making,and pharmaceutical beauty.It provides new ideas for the research and application of keratinase degradation mechanism.

关 键 词：角蛋白 生物酶解 降解机制 应用 

分 类 号：X713[环境科学与工程—环境工程]