非小细胞肺癌患者术后发生持续性肺不张的影响因素  

Influencing factors of postoperative persistent atelectasis in patients with non-small cell lung cancer

作　　者：武晓单 于慧敏 朱长庚[1] WU Xiaodan;YU Huimin;ZHU Changgeng(Department of Cardiothoracic Surgery of Sixth People’s Hospital of Zhengzhou,Zhengzhou 450000 Henan,China)

机构地区：[1]郑州市第六人民医院胸心外科,河南郑州450000

出　　处：《中国民康医学》2025年第6期9-11,15,共4页Medical Journal of Chinese People’s Health

摘　　要：目的:探讨非小细胞肺癌患者术后发生持续性肺不张的影响因素。方法:回顾性分析2019年1月至2024年1月该院收治的70例进行胸腔镜手术治疗的非小细胞肺癌患者的临床资料,按照术后是否发生持续性肺不张将其分为发生组(n=21)和未发生组(n=49)。统计患者基线资料,采用Logistic回归分析非小细胞肺癌患者术后发生持续性肺不张的影响因素。结果:两组性别、年龄、合并高血压病、合并糖尿病、吸烟史、肺炎史、肿瘤部位、术式比较,差异均无统计学意义(P>0.05);两组体质量指数、合并慢性阻塞性肺疾病(COPD)、手术时间、麻醉方式、气管插管比较,差异均有统计学意义(P<0.05);Logistic回归分析结果显示,体质量指数≥23 kg/m^(2)、合并COPD、手术时间≥3 h、全身麻醉、气管插管均为非小细胞肺癌患者术后发生持续性肺不张的危险因素(OR>1,P<0.05)。结论:体质量指数≥23 kg/m^(2)、合并COPD、手术时间≥3 h、全身麻醉、气管插管均为非小细胞肺癌患者术后发生持续性肺不张的危险因素。Objective:To investigate influencing factors of postoperative persistent atelectasis in patients with non-small cell lung cancer.Methods:The clinical data of 70 patients with non-small cell lung cancer who underwent thoracoscopic surgery in the hospital from January 2019 to January 2024 were retrospectively analyzed.According to whether persistent atelectasis occurred after the surgery,they were divided into occurrence group(n=21)and non-occurrence group(n=49).The clinical data of patients were statistically analyzed.Logistic regression was used to analyze the influencing factors of postoperative persistent atelectasis in the patients with non-small cell lung cancer.Results:There were no significant differences in gender,age,combined hypertension,combined diabetes,smoking history,pneumonia history,tumor location and surgical procedure between the two groups(P>0.05).There were significant differences in body mass index,chronic obstructive pulmonary disease(COPD),operation time,anesthesia method and tracheal intubation between the two groups(P<0.05).Logistic regression analysis showed that body mass index≥23 kg/m^(2),COPD,operation time≥3 h,general anesthesia and tracheal intubation were risk factors for postoperative persistent atelectasis in the patients with non-small cell lung cancer(OR>1,P<0.05).Conclusions:Body mass index≥23 kg/m^(2),COPD,operation time≥3 h,general anesthesia and tracheal intubation are the risk factors for postoperative persistent atelectasis in the patients with non-small cell lung cancer.

关 键 词：非小细胞肺癌 胸腔镜手术 持续性肺不张 影响因素 

分 类 号：R734.2[医药卫生—肿瘤]