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作 者:黄福杨 张蔓 任海林[1] Huang Fuyang;Zhang Man;Ren Hailin(Department of Urology,Qinghai University Affiliated Hospital,Xining,Qinghai 810000,China;Department of Oncology,Qinghai University Affiliated Hospital,Xining,Qinghai 810000,China)
机构地区:[1]青海大学附属医院泌尿外科,青海西宁810000 [2]青海大学附属医院肿瘤内科,青海西宁810000
出 处:《中国药物与临床》2025年第6期403-408,共6页Chinese Remedies & Clinics
摘 要:前列腺癌是全球男性中发病率最高的癌症之一,内分泌治疗能够抑制肿瘤进展,但其对患者体能状态的负面影响逐渐引起广泛关注,尤其是疲劳、肌肉萎缩及运动能力下降等问题。现有研究多集中于短期疗效,缺乏长期随访数据,并且研究方法存在差异。本文综述内分泌治疗对前列腺癌患者体能状态的影响,探讨主要影响因素,并提出改善患者生活质量和治疗依从性的建议。Prostate cancer is one of the most common cancers among men worldwide.Although endocrine therapy significantly inhibits tumor progression,its negative impact on patients'physical performance has increas-ingly garnered attention,particularly regarding fatigue,muscle atrophy,and reduced physical capacity.Current studies predominantly focus on short-term efficacy,with limited long-term follow-up data and inconsistent research methods.This review summarizes the effects of endocrine therapy on the physical performance of prostate cancer patients,explores the main contributing factors,and provides recommendations to improve patients'quality of life and treatment adherence.
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