牙周非手术治疗对老年牙周病伴2型糖尿病患者血糖、糖化血红蛋白的影响  

Effects of non-surgical periodontal treatment on blood glucose and glycosylated hemoglobin in elderly patients with periodontal disease and type 2 diabetes mellitus

作　　者：关敏 GUAN Min(Inner Mongolia Autonomous Region People's Hospital,Hohhot 010017,China)

机构地区：[1]内蒙古自治区人民医院,010017

出　　处：《中国现代药物应用》2025年第5期46-49,共4页Chinese Journal of Modern Drug Application

摘　　要：目的分析牙周非手术治疗对老年牙周病伴2型糖尿病患者血糖、糖化血红蛋白(HbA1c)的影响。方法选择200例老年牙周病伴2型糖尿病患者,均给予牙周非手术治疗。比较患者治疗前后血糖指标[空腹血糖(FBG)、餐后2 h血糖(2 h PG)、糖化血红蛋白]、炎症指标(肿瘤坏死因子-α、超敏C反应蛋白、白细胞介素-6)、疼痛评分、牙周指标[牙周探诊深度(PD)、龈沟出血指数(BI)],统计分析患者治疗效果、不良反应发生情况。结果患者治疗后FBG(5.21±1.01)mmol/L、2 h PG(9.80±1.71)mmol/L、糖化血红蛋白(6.22±1.59)%、肿瘤坏死因子-α(1.52±0.21)ng/L、超敏C反应蛋白(7.12±1.02)mg/L、白细胞介素-6(61.22±2.16)pg/ml均低于治疗前的(9.21±3.55)mmol/L、(12.37±4.72)mmol/L、(11.35±1.92)%、(3.75±0.31)ng/L、(13.25±3.21)mg/L、(162.21±16.71)pg/ml(P<0.05)。患者治疗后疼痛评分(1.19±0.12)分低于治疗前的(5.25±1.28)分(t=44.661,P<0.05)。患者治疗后PD为(1.12±0.14)mm、BI为(1.21±0.15)分,均低于治疗前的(4.12±1.21)mm和(4.34±1.28)分(t=34.831、34.347,P<0.05)。200例患者经过治疗,总有效率为100%,其中治愈167例,有效33例,无效0例。200例患者治疗过程中未见不良反应。结论牙周非手术治疗对于老年牙周病伴2型糖尿病患者的治疗效果确切,可缓解疼痛程度,控制炎症,改善牙周健康,且有利于控制血糖和糖化血红蛋白水平,值得推广。Objective To analyze the effects of non-surgical periodontal treatment on blood glucose and glycosylated hemoglobin(HbA1c)in elderly patients with periodontal disease and type 2 diabetes mellitus.Methods A total of 200 elderly patients with periodontal disease and type 2 diabetes mellitus were selected.All patients were given non-surgical periodontal treatment.Comparison of blood glucose indexes[fasting blood glucose(FBG),2 h postprandial glucose(2 h PG),glycosylated hemoglobin],inflammatory indexes(tumor necrosis factor-α,hypersensitive C-reactive protein,interleukin-6),pain scores,periodontal indexes[probing depth(PD),bleeding index(BI)]before and after treatment;analysis of the therapeutic effect and occurrence of adverse reactions.Results After treatment,patients had FBG of(5.21±1.01)mmol/L,2 h PG of(9.80±1.71)mmol/L,glycosylated hemoglobin of(6.22±1.59)%,tumor necrosis factor-αof(1.52±0.21)ng/L,hypersensitive C-reactive protein of(7.12±1.02)mg/L,and interleukin-6 of(61.22±2.16)pg/ml,which were lower than(9.21±3.55)mmol/L,(12.37±4.72)mmol/L,(11.35±1.92)%,(3.75±0.31)ng/L,(13.25±3.21)mg/L,and(162.21±16.71)pg/ml before treatment(P<0.05).The pain score of the patients after treatment was(1.19±0.12)points,which was lower than(5.25±1.28)points before treatment(t=44.661,P<0.05).PD and BI of the patients were(1.12±0.14)mm and(1.21±0.15)min after treatment,both were lower than(4.12±1.21)mm and(4.34±1.28)min before treatment(t=34.831,34.347;P<0.05).200 patients underwent treatment,with a total effective rate of 100%.Among them,167 cases were cured,33 cases were effective,and 0 cases were ineffective.No adverse reactions were observed during the treatment process.Conclusion Non-surgical periodontal treatment is effective for elderly patients with periodontal disease and type 2 diabetes mellitus.It can alleviate pain level,control inflammation,improve periodontal health,and help control levels of blood glucose and glycosylated hemoglobin.It is worth promoting.

关 键 词：牙周非手术治疗 2型糖尿病 牙周病 血糖 糖化血红蛋白 老年 

分 类 号：R78[医药卫生—口腔医学]