系统性疾病致甲改变机制研究进展  

Pathogenesis of nail damages secondary to systemic diseases

作　　者：蒋佳怡 王大光[1] Jiang Jiayi;Wang Daguang(Department of Dermatology,the First Affiliated Hospital with Nanjing Medical University,Nanjing 210029,China)

机构地区：[1]南京医科大学第一附属医院皮肤科,南京210029

出　　处：《中华皮肤科杂志》2025年第3期282-285,共4页Chinese Journal of Dermatology

基　　金：国家自然科学基金(81000703、81472896);江苏省自然科学基金(BK2009437);江苏省“六大人才高峰”C类资助项目(2015-WSW-026)。

摘　　要：系统性疾病往往造成甲损害,如杵状指、匙状甲、裂片状出血、白甲、黄甲以及毕氏线等。这些甲改变可为系统性疾病的诊断提供线索。但目前对于系统性疾病所致的甲损害研究较少,机制不明,本文总结该类疾病发生机制的研究进展,为诊断及治疗提供帮助。Many nail changes have been found to be associated with systemic diseases,such as acropachy,koilonychia,splinter hemorrhages,leukonychia,yellow nail syndrome,Beau′s lines,etc.,so they may provide clues for the diagnosis of systemic disorders.However,studies on nail damages secondary to systemic diseases are rare,and their pathogenesis is still unclear.This review summarizes the progress in the pathogenesis of nail damages in systemic diseases,so as to improve their diagnosis and treatment.

关 键 词：指(趾)甲疾病 杵状指 黄甲综合征 匙状甲 裂片状出血 系统性疾病 发病机制 

分 类 号：R73[医药卫生—肿瘤]