Continuous normothermic machine perfusion of donor livers in the United States:the challenging road from the trial-world into the real-world  

作　　者：Otto B.van Leeuwen Philipp Dutkowski Diethard Monbaliu Vincent E.de Meijer 

机构地区：[1]Department of Surgery,UMCG Comprehensive Transplant Center,University of Groningen and University Medical Center Groningen,Groningen,The Netherlands [2]Department of Visceral Surgery,University Hospital Basel,Basel,Switzerland [3]Department of Abdominal Transplant Surgery,University Hospitals Leuven,Leuven,Belgium

出　　处：《Hepatobiliary Surgery and Nutrition》2024年第6期1022-1026,共5页肝胆外科与营养(英文)

摘　　要：Over the past decade,various liver machine perfusion techniques have been clinically implemented worldwide(Figure 1).Currently,there are two main ex situ liver perfusion techniques:hypothermic oxygenated perfusion and normothermic oxygenated perfusion.In the United States(U.S.),hypothermic machine perfusion was initially pioneered by James Guerrera.Meanwhile,clinical practice has largely shifted towards normothermic machine perfusion(NMP)(1).This shift is due to U.S.Food and Drug Administration(FDA)approval of normothermic devices and recent groundbreaking randomized controlled trials(RCTs)(Table 1).Recently,Chapman et al.

关 键 词：Liver transplantation machine perfusion normothermic machine perfusion(NMP) randomized controlled trial(RCT) 

分 类 号：R57[医药卫生—消化系统]