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作 者:雷洋[1] 李玉丽 谢孝明 刘珍[1] 张尚华[1] 蔡铁如[1] 谭英[1] 周卫强[1] 易钊旭[1] 唐云[2] LEI Yang;LI Yuli;XIE Xiaoming;LIU Zhen;ZHANG Shanghua;CAI Tieru;TAN Ying;ZHOU Weiqiang;YI Zhaoxu;TANG Yun(Institute of Literature and Information,Hunan Academy of Chinese Medicine,Changsha 410006,China;The First Affiliated Hospital of Hunan University of Chinese Medicine,Changsha 410007,China)
机构地区:[1]湖南省中医药研究院文献信息研究所,长沙410006 [2]湖南中医药大学第一附属医院,长沙410007
出 处:《中国实验方剂学杂志》2025年第7期182-190,共9页Chinese Journal of Experimental Traditional Medical Formulae
基 金:国家中医药博物馆委托课题(NMTCM-WT-ZC-2023-04);湖南省中医药防治新型冠状病毒肺炎专项(KYGG09);湖南省科技普惠性政策与创新环境建设计划项目(2020ZK4069)。
摘 要:经典名方桔梗汤是治疗咽痛、咳嗽的基本方。该文通过查询数据库,系统梳理与总结数据资料,采用文献计量学方法对桔梗汤的药物组成、炮制、制法与临床应用等关键信息进行考证分析。经考证,桔梗汤始载于《伤寒杂病论》,又称“甘桔汤”,后世各朝代医家的不断继承和创新桔梗汤多根据该方进行加减。该方的药物基原基本清晰,桔梗为桔梗科植物Platycodon grandiflorum的干燥根,甘草为豆科植物甘草Glycyrrhiza uralensis的干燥根和根茎,二药均选用生品。药物剂量为甘草27.60 g,桔梗13.80 g,加水600 mL,同煎至200 mL,饭后温服,每日2次,每次100 mL。桔梗汤主治少阴客热证型,以咳嗽、咽痛为其核心症状。桔梗汤在现代临床主要应用于呼吸系统疾病,如咽喉炎、食管炎、扁桃体炎、肺脓肿,尤其对咽喉炎、肺脓肿疾病疗效显著。该研究可为经典名方桔梗汤的现代临床应用与开发,提供文献基础。Jiegengtang is a basic formula for treating sore throat and cough.By means of bibliometrics,this study conducted a textual research and analysis on the key information such as formula origin,decocting methods,and clinical application of Jiegengtang.After the research,it can be seen that Jiegengtang is firstly contained in Treatise on Febrile and Miscellaneous Disease,which is also known as Ganjietang,and it has been inherited and innovated by medical practitioners of various dynasties in later times.The origins of Chinese medicines in this formula is basically clear,Jiegeng is the dried roots of Platycodon grandiflorum,Gancao is the dried roots and rhizomes of Glycyrrhiza uralensis,the two medicines are selected raw products.The dosage is 27.60 g of Glycyrrhizae Radix et Rhizoma and 13.80 g of Platycodonis Radix,decocted with 600 mL of water to 200 mL,taken warmly after meals,twice a day,100 mL for each time.In ancient times,Jiegengtang was mainly used for treating Shaoyin-heat invasion syndrome,with cough and sore throat as its core symptoms.In modern clinical practice,Jiegengtang is mainly used for respiratory diseases such as pharyngitis,esophagitis,tonsillitis and lung abscess,especially for pharyngitis and lung abscess with remarkable efficacy.This paper can provide literature reference basis for the modern clinical application and new drug development of Jiegengtang.
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