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作 者:吴梅 陈莉丽[1] 崔玉霞[1] 毛惠莹 吴玮 张建男[1] WU Mei;CHEN Lili;CUI Yuxia;MAO Huiying;WU Wei;ZHANG Jianan(Department of Neurosurgery,Jiangsu Subei People's Hospital,Yangzhou 225001,China)
出 处:《中国老年保健医学》2025年第1期136-139,共4页Chinese Journal of Geriatric Care
基 金:江苏省苏北人民医院科研基金一般项目(编号:SBHL22031)。
摘 要:脑肿瘤属于高死亡率、高致残率疾病,是威胁人类健康的难题,一般手术治疗是脑肿瘤的首选治疗方案。谵妄是脑肿瘤患者术后常见的并发症,常发生在术后1周内,表现为定向力障碍、认知障碍和意识水平下降。脑肿瘤患者术后发生谵妄不仅延长住院时间、增加医疗费用、延迟康复,还会提高跌倒风险,严重者危及患者生命。因此早期识别高危人群并针对性干预具有重大意义。本文通过系统检索国内外的相关文献,阐述了术后谵妄发生机制,明确了影响脑肿瘤患者术后谵妄的影响因素,包括年龄、教育水平、肿瘤恶性程度、肿瘤大小、肿瘤位置、患者心理、睡眠状态等,同时对脑肿瘤患者术后谵妄(POD)的药物干预和非药物干预进行论述,以期为早期识别和干预提供参考。Brain tumors are diseases characterized by high mortality and disability rates,posing a significant threat to human life and health.Surgery remains the most effective treatment for brain tumors.However,postoperative delirium(POD)is a common complication among brain tumor patients,typically occurring within the first week after surgery.This condition is characterized by disorientation,cognitive impairment,and reduced levels of consciousness.Postoperative delirium in brain tumor patients not only prolongs hospital stays and increases healthcare costs but also delays recovery and raises the risk of adverse events such as falls.In severe cases,it can even be life-threatening.Therefore,early identification of high-risk individuals and timely intervention are of paramount importance.This article systematically reviews relevant domestic and international literature to explore the mechanisms underlying postoperative delirium and to identify its influencing factors in brain tumor patients.These factors include age,education level,tumor malignancy,tumor size,tumor location,psychological state,and sleep quality.Additionally,the article examines both pharmacological and non-pharmacological interventions for postoperative delirium in this patient population,aiming to provide a reference for early identification and effective intervention strategies.
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