有氧运动对精神分裂症稳定期患者精神症状及糖脂代谢的影响  

Effects Of Aerobic Exercise on Psychiatric Symptoms and Glycolipid Metabolism in Stabilized Patients with Schizophrenia

作　　者：高晓奇[1] 冯芳[1] 李克松[1] 刘佳荣[1] 安然[1] 陈英男 苏秀茹[1] 关恒永[1] GAO Xiaoqi;FENG Fang;LI Kesong(Rongjun Hospital,Hebei Province,Baoding 071000,China)

机构地区：[1]河北省荣军医院,保定071000

出　　处：《国际精神病学杂志》2025年第1期43-46,共4页Journal Of International Psychiatry

基　　金：保定市科技计划项目(编号:2041ZF329)。

摘　　要：目的 探讨有氧运动对精神分裂症(Schizophrenia,SZ)稳定期患者精神症状及糖脂代谢的影响。方法 选择2020年11月~2021年11月116例男性SZ稳定期患者,利用数字表随机分组,两组均采用抗精神病药物治疗,对照组给予一般运动干预,观察组在对照组基础上给予有氧运动,干预时间均为6个月。比较干预前后SZ相关精神症状以及血糖、血脂水平。结果 干预后两组SZ精神症状评分均显著下降,且治疗后观察组阴性症状低于对照组(P<0.05),其他症状评分差异无统计学意义(P>0.05);干预后对照组空腹、餐后2h血糖、甘油三脂、总胆固醇无明显改善(P>0.05),干预后观察组均低于干预前且低于对照组(P<0.05)。结论 有氧运动能够进一步缓解SZ稳定期患者阴性症状,并降低血糖、血脂水平。Objective To investigate the effects of aerobic exercise on psychiatric symptoms and glycolipid metabolism in stable patients with schizophrenia(SZ).Methods A total of 116 male patients with stable SZ were selected from November 2020 to November 2021 and randomly grouped using a numerical table.Both groups were treated with antipsychotic drugs,the control group was given general exercise intervention,and the observation group was given aerobic exercise on the basis of the control group,and the intervention time was 6 months.SZ-related psychiatric symptoms as well as blood glucose and lipid levels were compared before and after the intervention.Results The SZ psychiatric symptom scores decreased significantly in both groups after the intervention,and the negative symptoms were lower in the observation group than in the control group after treatment(P<0.05).The difference in other symptom scores was not statistically significant(P>0.05).There was no significant improvement in fasting,postprandial 2h blood glucose,triglyceride and total cholesterol in the control group after intervention(P>0.05).All of them were lower in the observation group after the intervention than before the intervention and lower than in the control group(P<0.05).Conclusion Aerobic exercise can further alleviate negative symptoms and reduce blood glucose and lipid levels in patients with stable SZ.

关 键 词：有氧运动 精神分裂症 稳定期 精神症状 糖脂代谢 

分 类 号：R749.3[医药卫生—神经病学与精神病学]