COPD急性加重患者出现抑郁情绪的危险因素  

The Influencing Factors of Depression in patients Acute Exacerbation of Chronic Obstructive Pulmonary Disease

作　　者：施波 汪蔓[2] 罗丰平 SHI Bo;WANG Man;LUO Fengping(Department of Critical Care Medicine,Lujiang Branch of Shanghai East Hospital Affiliated to Tongji University,Hefei 231500,China)

机构地区：[1]同济大学附属东方医院庐江分院重症医学科,合肥231500 [2]合肥职业技术学院护理教研室

出　　处：《国际精神病学杂志》2025年第1期186-188,201,共4页Journal Of International Psychiatry

基　　金：安徽省高等学校科学研究项目(编号:2022AH052224)。

摘　　要：目的 探讨慢性阻塞性肺病(Chronic obstructive pulmonary disease,COPD)急性加重患者抑郁情绪的影响因素。方法 选择2020年7月~2023年6月92例COPD急性加重患者为观察对象,对患者进行抑郁情绪评估。比较抑郁组、无抑郁组的肺功能、年龄等资料,采用Logistic回归分析探讨抑郁情绪的影响因素。结果 在92例COPD急性加重患者检出有抑郁情绪的患者30例;抑郁组与无抑郁组的最大肺活量(Forced vital capacity,FEV)、一秒用力呼气容积(Forced expiratory volume in one second,FEV1)、药物不良反应、治疗效果、家庭收入、合并低氧血症、居住地、年龄具有统计学差异(P<0.05),两组的性别、婚姻、学历、营养不良无统计学差异(P>0.05);Logistic回归分析发现FEV、FEV1、药物不良反应、治疗效果差、家庭收入低、合并低氧血症是抑郁情绪的影响因素。结论 COPD急性加重患者较常出现抑郁情绪,FEV差、FEV1差、家庭收入低等会增加抑郁情绪的发生风险。Objective To explore the influencing factors of depression during acute exacerbation of chronic obstructive pulmonary disease(COPD).Methods Ninety-two patients with acute exacerbation of COPD from July 2020 to June 2023 were selected as the observation subjects,and the patients'depression was assessed.Lung function,age,and other medical records were compared between the depressed group and the non-depressed group.Logistic regression analysis was used to explore the influencing factors of depression.Results Depressive mood was detected in 30 out of 92 patients with acute exacerbation of COPD.There were statistically significant differences between the depression group and the non-depression group in tforced vital capacity(FEV),forced expiratory volume in one second(FEV1),adverse drug reactions,treatment effect,family income,hypoxemia,place of residence,and age(P<0.05).There were no statistically significant differences in gender,marriage,education,and malnutrition between the two groups(P>0.05).Logistic regression analysis found that FEV,FEV1,adverse drug reaction,poor treatment effect,low family income,combined with hypoxemia were the influencing factors of depressive mood.Conclusion Depression is more common in patients with acute exacerbation of COPD,and poor FEV,FEV1,and low family income increase the risk of depression.

关 键 词：慢性阻塞性肺病急性加重 抑郁情绪 影响因素 

分 类 号：R749.2[医药卫生—神经病学与精神病学]