胃食管反流患者焦虑状况及其与临床症状的关系  

Occurrence of anxiety in patients with gastroesophageal reflux disease and its relationship with clinical symptoms

作　　者：李东方 陈佳佳 段铮[2] LI Dongfang;CHEN Jiajia;DUAN Zheng(Zhumadian Central Hospital,Zhumadian 463000,China)

机构地区：[1]驻马店市中心医院,驻马店463000 [2]河南省中医院

出　　处：《国际精神病学杂志》2025年第1期237-239,共3页Journal Of International Psychiatry

基　　金：国家中医临床研究基地科研专项课题(编号:2019JDZX024)。

摘　　要：目的 探讨胃食管反流病(Gastroesophageal reflux disease,GERD)焦虑情况及与临床症状的关系。方法 以2022年2月~2024年2月113例GERD患者为研究对象,采用汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA)评估患者焦虑情绪,设焦虑组、正常组。比较两组一般资料、胃食管反流病诊断问卷(Reflux disease questionnaire,RDQ)、GERD生活质量量表(Quality of life scale for GERD,GERD-HRQL),分析焦虑组患者HAMA评分与RDQ评分的相关性。结果 113例患者中32例具有焦虑情绪,发生率28.32%;两组病程、学历具有显著性差异(P<0.05),两组性别、年龄、体质指数无显著性差异(P>0.05);焦虑组RDQ评分、GERD-HRQL评分均高于正常组(P<0.05);焦虑组患者HAMA评分与RDQ评分、GERD-HRQL评分呈正相关关系。结论 GERD焦虑情绪发生率较高,并且焦虑情绪与临床症状以及相关生活质量存在显著的相关性,可能相互影响。Objective To explore the occurrence of anxiety in gastroesophageal reflux disease(GERD)and its relationship with clinical symptoms.Methods A total of 113 GERD patients from February 2022 to February 2024 were selected as the study subjects.The Hamilton Anxiety Scale(HAMA)were used to assess patient anxiety,and were set as the anxiety group and normal group.The two sets of general information,Reflux Disease Questionnaire(RDQ),and GERD Quality of Life Scale for GERD(GERD-HRQL)were compared.The correlation between HAMA score and RDQ score in anxiety group patients were analyzed.Results Out of 113 patients,32 had anxiety,with an anxiety rate of 29.63%.There is a significant difference in the course of illness and educational background between the two groups(P<0.05).There was no significant difference in gender,age,and body mass index between the two groups(P>0.05).The RDQ score and GERD-HRQL score of the anxiety group were higher than those of the normal group(P<0.05).There is positive correlation between HAMA score,RDQ score,and GERD-HRQL score in anxiety group patients.Conclusion GERD has a high incidence of anxiety,and there is a significant correlation between anxiety and clinical symptoms as well as related quality of life,which may affect each other.

关 键 词：胃食管反流病 焦虑 临床症状 生活质量 

分 类 号：R749[医药卫生—神经病学与精神病学]