接受放化疗的恶性消化系统肿瘤患者抑郁情绪的影响因素  

The influencing factors on depression in patients with malignant digestive system tumors undergoing radiotherapy and chemotherapy

作　　者：柳浩然[1] 王建华[1] 李甲 王鑫[1] 王锦辉[1] LIU Haoran;WANG Jianhua;LI Jia(Tangshan People's Hospital,Tangshan 063000,China)

机构地区：[1]唐山市人民医院,唐山063000

出　　处：《国际精神病学杂志》2025年第1期245-248,310,共5页Journal Of International Psychiatry

基　　金：河北省医学科学研究课题计划(编号:20191621)。

摘　　要：目的 分析恶性消化系统肿瘤放化疗患者抑郁情绪的影响因素。方法 选取2020年5月~2023年5月于本院行放化疗的恶性消化系统肿瘤患者99例作为研究对象,根据汉密尔顿抑郁量表评分分为抑郁组(n=55)和无抑郁组(n=44)。收集比较两组患者临床资料,并采用多因素Logistic回归分析明确影响恶性消化系统肿瘤放化疗患者抑郁情绪产生的危险因素。结果 抑郁组患者和无抑郁组患者诊断分级、放化疗次数、家庭月收入、家庭功能、社会支持度、血清白蛋白、血红蛋白等比较,差异均有统计学意义(P<0.05)。Logistic多因素回归分析显示:诊断分级、放化疗次数、家庭月收入、家庭功能、社会支持度、血清白蛋白、血红蛋白均是影响恶性消化系统肿瘤放化疗患者抑郁情绪产生的独立因素(P<0.05)。结论 恶性消化系统肿瘤放化疗患者抑郁情绪产生受诊断分级、放化疗次数、家庭月收入、家庭功能、社会支持度、血清白蛋白、血红蛋白等因素的影响,其中家庭功能和社会支持度高、血清白蛋白和血红蛋白水平高是保护因素。Objective Analyze the influencing factors of depression in patients with malignant digestive system tumors undergoing radiotherapy and chemotherapy.Methods 99 patients with malignant digestive system tumors who underwent radiotherapy and chemotherapy in our hospital from May 2020 to May 2023 were selected as the study subjects.According to the Hamilton Depression Rating Scale(HAMD)score,they were divided into a depression group(n=55)and a non depression group(n=44).Collect and compare clinical data of two groups of patients,and use multiple logistic regression analysis to identify the risk factors affecting depression in patients with malignant digestive system tumors undergoing radiotherapy and chemotherapy.Results The diagnostic grade,frequency of radiotherapy and chemotherapy,monthly family income,family function,social support,serum albumin,hemoglobin,and other factors were compared between the depression group and the non depression group,and the differences were statistically significant(P<0.05).Logistic multiple regression analysis showed that diagnostic grade,frequency of radiotherapy and chemotherapy,monthly family income,family function,social support,serum albumin,and hemoglobin were all independent factors affecting the development of depression in patients with malignant digestive system tumors undergoing radiotherapy and chemotherapy(P<0.05).Conclusion The occurrence of depression in patients with malignant digestive system tumors undergoing radiotherapy and chemotherapy is influenced by factors such as diagnostic grade,frequency of radiotherapy and chemotherapy,monthly family income,family function,social support,serum albumin,hemoglobin,etc.Among them,high family function and social support,high serum albumin and hemoglobin levels are protective factors.

关 键 词：恶性消化系统肿瘤 放化疗 抑郁情绪 血清白蛋白 血红蛋白 社会支持度 家庭功能 

分 类 号：R749.2[医药卫生—神经病学与精神病学]