Harnessing cellulose-binding protein domains for the development of functionalized cellulose materials  

作　　者：Shaowei Li Guodong Liu 

机构地区：[1]Taishan College,School of Life sciences,Shandong University,72 Binhai Road,Qingdao,Shandong 266237,China [2]State Key Laboratory of Microbial Technology,Shandong University,72 Binhai Road,Qingdao,Shandong 266237,China

出　　处：《Bioresources and Bioprocessing》2024年第1期990-999,共10页生物资源与生物加工(英文)

基　　金：supported by the National Natural Science Foundation of China(32170037)and SKLMT Frontiers and Challenges Project(SKLMTFCP-2023-04).

摘　　要：Cellulosic materials are attracting increasing research interest because of their abundance,biocompatibility,and biodegradability,making them suitable in multiple industrial and medical applications.Functionalization of cellulose is usually required to improve or expand its properties to meet the requirements of different applications.Cellulose-binding domains(CBDs)found in various proteins have been shown to be powerful tools in the functionalization of cellulose materials.In this review,we firstly introduce the structural characteristics of commonly used CBDs belonging to carbohydrate-binding module families 1,2 and 3.Then,we summarize four main kinds of methodologies for employing CBDs to modify cellulosic materials(i.e.,CBD only,genetic fusion,non-covalent linkage and covalent linkage).Via different approaches,CBDs have been used to improve the material properties of cellulose,immobilize enzymes for biocatalysis,and design various detection tools.To achieve industrial applications,researches for lowering the production cost of CBDs,improving their performance(e.g.,stability),and expanding their application scenarios are still in need.

关 键 词：Cellulosic materials Cellulose-binding protein Carbohydrate binding module Material functionalization 

分 类 号：G63[文化科学—教育学]