功能性寡糖缓解犊牛腹泻的机理研究进展  

Research Progress on the Mechanism of Functional Oligosaccharides Alleviating Calf Diarrhea

作　　者：张燕敏 刘帅 滕战伟[1,2] 谢红兵 夏小静[1,2] 贺永惠 常美楠[1,2] ZHANG Yanmin;LIU Shuai;TENG Zhanwei;XIE Hongbing;XIA Xiaojing;HE Yonghui;CHANG Meinan(College of Animal Science and Veterinary Medicine,Henan Institute of Science and Technology,Xinxiang 453003,China;Branch Laboratory of the Key Laboratory of Animal Pathogens and Biosafety,Ministry of Education,Zhengzhou 450000,China)

机构地区：[1]河南科技学院动物科技学院,新乡453003 [2]动物病原与生物安全教育部重点实验室分室,郑州450000

出　　处：《畜牧兽医学报》2025年第3期979-994,共16页ACTA VETERINARIA ET ZOOTECHNICA SINICA

基　　金：河南省重点研发与推广专项(科技攻关)项目(232102111038,232102111039,232102111049)。

摘　　要：犊牛腹泻是养牛业面临的重要问题,其发病率高、死亡率高、防治成本高,甚至愈后易出现发育迟缓、生产性能低下等现象,威胁着养牛业的可持续发展。而功能性寡糖作为一类水溶性膳食纤维和具有双歧因子特性的益生元,被广泛应用于维护肠道健康。本文综述了功能性寡糖的结构、功能以及犊牛腹泻的致病因子,并重点阐述了功能性寡糖缓解犊牛腹泻的作用机理研究进展,将为促进犊牛肠道健康与功能性寡糖的合理利用提供重要参考。Calf diarrhea is an important issue faced by the cattle industry.It has high incidence and mortality rates,high prevention and treatment costs,and even developmental delays and reduced production performance after recovery,threatening the industry’s sustainable development.Functional oligosaccharides,as a type of water-soluble dietary fiber and prebiotics with bifidogenic properties,have been widely used for maintaining intestinal health.This article reviews the structure and function of functional oligosaccharides,as well as the factors that cause calf diarrhea.It also highlights the progress of research on the mechanism of functional oligosaccharides in alleviating calf diarrhea.These contents will provide an important reference for promoting calf intestinal health and the rational utilization of functional oligosaccharides.

关 键 词：功能性寡糖 犊牛腹泻 毒力机制 肠道菌群 免疫功能 

分 类 号：S823.5[农业科学—畜牧学]