2005-2022年我国急性出血性结膜炎发病的长期趋势  

Long⁃term trend of acute hemorrhagic conjunctivitis in China from 2005 to 2022

作　　者：赵文文 韦弥青 苏永健 张家玮 戴诗燕 李海 ZHAO Wenwen;WEI Miqing;SU Yongjian;ZHANG Jiawei;DAI Shiyan;LI Hai(Teaching and Researching Section of Epidemiology,School of Public Health and Management,Guangxi University of Chinese Medicine,Nanning,Guangxi 530200,China;Guangxi Key Laboratory of Translational Medicine for Treating High incidence Infectious Diseases with Integrative Medicine,Guangxi University of Chinese Medicine,Nanning,Guangxi 530200,China;Preventive Medicine Center of Ruikang Hospital,Guangxi University of Chinese Medicine,Nanning,Guangxi 530011,China)

机构地区：[1]广西中医药大学公共卫生与管理学院流行病学教研室,广西南宁530200 [2]广西中医药大学广西高发传染病中西医结合转化医学重点实验室,广西南宁530200 [3]广西中医药大学附属瑞康医院治未病中心,广西南宁530011

出　　处：《热带医学杂志》2025年第1期124-128,I0003,共6页Journal of Tropical Medicine

基　　金：广西中医药大学高层次公共卫生人才培育创新团队项目(2022A009);广西中医药大学桂派杏林拔尖人才项目(2022C010)。

摘　　要：目的分析我国急性出血性结膜炎(AHC)发病的长期趋势,为AHC的防控提供参考依据。方法收集中国疾病预防控制中心公共卫生科学数据中心的AHC监测数据,采用Joinpoint回归模型分析我国各省份、各年龄组AHC发病的长期趋势。结果2005-2022年我国共报告AHC 833338例,年平均报告发病率为3.4115/10万。2005-2022年我国AHC发病率变化趋势总体上较为平稳,平均年度变化百分比(AAPC)为5.60%(P=0.747)。AHC报告发病率的变化趋势分为3个阶段。第一阶段(2005-2010年)发病率上升显著,年度变化百分比(APC)为70.36%(P=0.038);第二阶段(2010-2013年)发病率较为平稳,APC为-44.13%(P=0.518);第三阶段(2013-2022年)发病率基本平稳,APC为0.10%(P=0.986)。2005-2018年间,AHC的年平均报告发病率(≥5.0000/10万)居前6位的省份为广西、海南、广东、重庆、湖北和浙江,AHC发病率呈上升趋势有9个省份(安徽、甘肃、河南、陕西、贵州、河北、青海、山东和山西)(P均≤0.05),呈现为下降趋势有4个省份(上海、天津、北京、新疆)(P均≤0.05),其余省份的发病率变化趋势较为平稳(P均>0.05);AHC在0~<20岁儿童高发(占总发病人数的41.36%),年平均报告发病率最高为3~<4岁组,有3个年龄组(65~<70岁组、75~<80岁组、80~<85岁组)的发病率变化呈上升趋势(P均≤0.05),AAPC上升幅度范围为14.75%~16.24%;其余23个年龄组发病率的变化趋势保持平稳(P均>0.05)。结论我国AHC发病率变化趋势总体上较为平稳,但不同省份和年龄组的变化趋势有所不同,各地区有关部门应根据不同省份及年龄组的发病趋势制定相对应的防控手段。Objective To analyze the long-term trend of acute hemorrhagic conjunctivitis(AHC)in China and provide reference for the prevention and control of AHC.Methods AHC monitoring data was collected from the Public Health Science Data Center of the Chinese Center for Disease Control and Prevention,and the Joinpoint regression model was used to analyze the long-term trend of AHC incidence in various provinces and age groups in China.Results From 2005 to 2022,a total of 833338 cases of AHC were reported in China,with an annual average reported incidence rate of 3.4115/100000.From 2005 to 2022,the trend of AHC incidence in China was generally stable,and the average annual percent change(AAPC)was 5.60%(P=0.747).The trend of incidence rate reported by AHC could be divided into three stages.In the first stage(2005-2010),the incidence rate increased significantly,with annual percent change(APC)of 70.36%(P=0.038);in the second stage(2010-2013),the incidence rate was relatively stable,APC was-44.13%(P=0.518);in the third stage(2013-2022),the incidence rate was relatively stable,and the APC was 0.10%(P=0.986).From 2005 to 2018,the top six provinces with the annual average reported incidence rate of AHC(≥5.0000/100000)were Guangxi,Hainan,Guangdong,Chongqing,Hubei and Zhejiang.The incidence rate of AHC showed an upward trend in 9 provinces(Anhui,Gansu,Henan,Shaanxi,Guizhou,Hebei,Qinghai,Shandong and Shanxi)(all P≤0.05),a downward trend in 4 provinces(Shanghai,Tianjin,Beijing,Xinjiang)(all P≤0.05),and the incidence rate of the remaining provinces showed a relatively stable trend(all P>0.05).The incidence of AHC was high in children aged 0-<20 years old(41.36%of the total number of cases).The highest annual average incidence rate was reported in the 3-<4 year-old group.The incidence rate of three age groups(65-<70,75-<80,80-<85)showed an upward trend(all P≤0.05),and the range of increase of AAPC was 14.75%-16.24%.The change trend of incidence rate in the other 23 age groups remained stable(all P>0.05).Conclusions The change t

关 键 词：急性出血性结膜炎 Joinpoint回归模型 发病率 长期趋势 

分 类 号：R777.31[医药卫生—眼科]