氢质子磁共振波谱在儿童神经代谢性疾病中的应用现状  

Application status of 1H-MRS in children’s neurometabolic diseases

作　　者：邬江涛 钱龙 郭毅 刘虎 WU Jiangtao;QIAN Long;GUO Yi;LIU Hu(Department of Radiology,The Second Hospital of Jiaxing,Jiaxing,Zhejiang 314000,China)

机构地区：[1]嘉兴市第二医院放射科,浙江嘉兴314000

出　　处：《重庆医学》2025年第3期775-778,785,共5页Chongqing Medical Journal

基　　金：浙江省医药卫生科技计划项目(2021RC131)。

摘　　要：近年来儿童神经代谢性疾病的发病率日益增长,该疾病的临床诊断缺乏特异性,易发生漏诊、误诊,给社会和家庭带来沉重的精神及经济负担。氢质子磁共振波谱(^(1)H-MRS)可以无创检测、定量分析脑代谢物含量,间接反映脑代谢状态的变化情况,从而为儿童神经代谢性疾病的早期诊断及鉴别诊断提供影像学依据,在临床诊疗过程中发挥着越来越重要的作用。该文综述^(1)H-MRS在儿童神经代谢性疾病诊断、治疗及预后评估中的应用现状。In recent years,the incidence of neurometabolic diseases in children is increasing,the clinical diagnosis of this disease is lack of specificity,easy to occur missed diagnosis,misdiagnosis,which brings heavy mental and economic burden to society and family.Hydrogen proton magnetic resonance spectroscopy(^(1)H-MRS)can non-invasive detection and quantitative analysis of brain metabolite content,indirectly reflect the changes in brain metabolic state,and thus provide imaging basis for the early diagnosis and differential diagnosis of neurometabolic diseases in children,playing an increasingly important role in clinical diagnosis and treatment.This article focuses on the application of^(1)H-MRS in the diagnosis,treatment and prognosis assessment of neurometabolic diseases in children.

关 键 词：磁共振波谱 代谢物含量 儿童 神经代谢性疾病 

分 类 号：R741[医药卫生—神经病学与精神病学]