支气管动脉灌注化疗联合化疗栓塞术治疗老年中晚期肺癌的临床效果  

Clinical Effect of Bronchial Arterial Infusion Chemotherapy Combined with Chemoembolization in Treatment of Aged Middle-Late Stage Lung Cancer

作　　者：余小汉 吴瑕 宋红艳 Yu Xiaohan;Wu Xia;Song Hongyan(The People's Hospital of Yingshan,Huanggang 438700,Hubei Province,China)

机构地区：[1]黄冈市英山县人民医院,湖北黄冈438700

出　　处：《中国社区医师》2025年第7期30-32,共3页Chinese Community Doctors

摘　　要：目的:探讨支气管动脉灌注化疗联合化疗栓塞术治疗老年中晚期肺癌的临床效果。方法:选取2017年2月—2021年8月黄冈市英山县人民医院收治的120例老年中晚期肺癌患者进行研究,随机分为对照组和观察组,各60例。对照组给予支气管动脉灌注化疗,观察组在对照组基础上采用化疗栓塞术治疗。比较两组患者治疗有效率、生活质量及不良反应发生率。结果:观察组治疗总有效率高于对照组(P<0.05)。治疗前,两组患者生理、心理社会、婚姻关系、与医务人员的关系评分比较,差异无统计学意义(P>0.05);治疗后,两组生理、心理社会、婚姻关系、与医务人员的关系评分下降,且观察组低于对照组(P<0.05)。观察组患者不良反应总发生率为6.67%,低于对照组(P<0.05)。结论:支气管动脉灌注化疗联合化疗栓塞术治疗老年中晚期肺癌的临床效果较好,能够提升患者的生活质量,减少不良反应。Objective:To explore the clinical effect of bronchial arterial infusion chemotherapy combined with chemoembolization in the treatment of aged middle-late stage lung cancer.Methods:A total of 120 elderly patients with middle-late stage lung cancer admitted to the People's Hospital of Yingshan to Huanggang City from February 2017 to August 2021 were selected for study.They were randomly divided into control group and observation group,with 60 cases in each group.The control group was treated with bronchial arterial perfusion chemotherapy,and the observation group was treated with chemoembolization on the basis of the control group.The response rate,quality of life and incidence of adverse reactions were compared between the two groups.Results:The overall response rate in the observation group was higher than that in the control group(P<0.05).Before treatment,there was no statistically significant difference in the scores of physiology,psychosociety,marital relationship and relationship with medical staff between the two groups(P>0.05).After treatment,the scores of physiology,psychosociety,marital relationship and relationship with medical staff in the two groups decreased,and the scores in the observation group were lower than those in the control group(P<0.05).The total incidence of adverse reactions in the observation group was 6.67%,which was lower than that in the control group(P<0.05).Conclusion:Bronchial arterial infusion chemotherapy combined with chemoembolization has a good clinical effect in the treatment of aged middle-late stage lung cancer,and can improve the quality of life of patients and reduce adverse reactions.

关 键 词：支气管动脉灌注化疗 化疗栓塞术 老年 中晚期 肺癌 

分 类 号：R734.2[医药卫生—肿瘤]