肠道微生物对猪肌内脂肪沉积的调控研究  

Regulation of intramuscular fat deposition by intestinal microbes in pigs

作　　者：郑婉如 刘梦宽 吕欣宇 王雄 柏金宝 尹杰[2] 马杰 ZHENG WanRu;LIU MengKuan;LV XinYu;WANG Xiong;BAI JinBao;YIN Jie;MA Jie(College of Animal Science and Technology,Guangxi University,Nanning 530004,China;College of Animal Science and Technology,Hunan Agricultural University,Changsha,410128,China;Hunan Baodong Agriculture and Animal Husbandry Technology Co.,LTD,Shaoyang 422002,China)

机构地区：[1]广西大学动物科学技术学院,南宁530004 [2]湖南农业大学动物科学技术学院,长沙410128 [3]湖南宝东农牧科技股份有限公司,邵阳422002

出　　处：《中国科学:生命科学》2025年第3期479-488,共10页Scientia Sinica(Vitae)

摘　　要：肌内脂肪(intramuscular fat,IMF)是影响肉品质的重要因素,并且受到转录因子的联级调控.大量研究表明,肠道微生物及其代谢物在调控肌内脂肪沉积上发挥着重要作用,但其作用机制还不明确.本文重点介绍了肌纤维发育和肌内脂肪形成的机制,并进一步阐明肠道微生物通过Wnt/β-catenin,TGF-β-SMAD3,PPARγ及C/EBPα等几个重要信号通路对肌内脂肪代谢的作用机制,以期为调控猪肉品质提供干预靶点.Intramuscular fat(IMF)is an important factor affecting the quality of meat and regulated by transcriptional factors.Numerous studies have shown that gut microbiota and their metabolites play an important role in regulating IMF,but the mechanism is still unclear.This paper focuses on the mechanism of myofiber development and IMF formation,and further elucidates the mechanism of gut microbiota on IMF metabolism through several important signaling pathways such as Wnt/β-catenin,TGFβ-SMAD3,PPARγand C/EBPα.In order to provide intervention targets for regulating pork quality.

关 键 词：肠道微生物 猪 肌内脂肪 调控 

分 类 号：S828[农业科学—畜牧学]