胃癌保功能手术的发展现状和前景展望  

Development status and prospects of functional preservation surgery for gastric cancer

作　　者：邢继尧 苗儒林[1] 陕飞[1] 李子禹[1] Xing Jiyao;Miao Rulin;Shan Fei;Li Ziyu(Gastrointestinal Tumor Center,Peking University Cancer Hospital&Institute,Beijing Institute for Cancer Research,Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education),Beijing 100142,China)

机构地区：[1]北京大学肿瘤医院暨北京市肿瘤防治研究所胃肠肿瘤中心、恶性肿瘤发病机制及转化研究教育部重点实验室,北京100142

出　　处：《中华胃肠外科杂志》2025年第2期127-133,共7页Chinese Journal of Gastrointestinal Surgery

摘　　要：胃癌保功能手术是一种以改善术后功能为核心目标的治疗策略, 在确保肿瘤学安全性的前提下, 通过保留贲门、幽门和迷走神经等重要解剖结构以及消化、分泌、排空和抗反流等关键功能, 最大限度地减少对患者术后生活质量的负面影响。随着新辅助治疗模式的广泛应用和抗肿瘤药物疗效的不断提高, 保功能手术的应用前景和适应证范围也有望进一步拓展。本文从胃癌保功能手术的主要类型、新辅助治疗后的应用以及新技术探索等方面阐述其发展现状和未来前景。Function-preserving surgery for gastric cancer is a treatment strategy aimed at improving postoperative function while ensuring oncological safety.By preserving important anatomical structures such as the cardia,pylorus,and vagus nerve,as well as key functions like digestion,secretion,emptying,and anti-reflux,this approach aims to minimize the negative impact on patients'postoperative quality of life.With the widespread application of neoadjuvant treatment and the continuous improvement in the efficacy of anti-tumor drugs,the application and indications for functional-preserving surgery may further expand.This article reviews the current status and future prospects of function-preserving surgery for gastric cancer,focusing on its main types,applications after neoadjuvant therapy,and the exploration of new technologies.

关 键 词：胃肿瘤 保功能手术 新辅助治疗 

分 类 号：R73[医药卫生—肿瘤]