局部进展期胃癌新辅助免疫治疗后的胃保功能手术  

Function-preserving gastrectomy for locally advanced gastric cancer after neoadjuvantimmunotherapy

作　　者：王经杭 袁震 卫勃[1] Wang Jinghang;Yuan Zhen;Wei Bo(Department of General Surgery,the First Medical Center,Chinese PLA General Hospital,Beijing 100853,China)

机构地区：[1]解放军总医院第一医学中心普通外科医学部,北京100853

出　　处：《中华胃肠外科杂志》2025年第2期134-138,共5页Chinese Journal of Gastrointestinal Surgery

基　　金：国家自然科学基金(82073192,82273231);北京市科技计划项目(Z221100007422125)。

摘　　要：随着免疫治疗在局部进展期胃癌中的应用成为新热点,免疫治疗也开始融合进新辅助治疗方案中。新辅助治疗后越来越高的肿瘤降期率和病理完全缓解率使得胃保功能手术成为可能。本文旨在探讨新辅助治疗后胃保功能手术的可行性,从手术时机、淋巴结清扫、胃保功能手术方式以及观察等待等角度进行详细分析,希望为新辅助治疗后行胃保功能手术提供更多的参考依据。With the application of immunotherapy in locally advanced gastric cancer becoming a current research hotspot,the organic integration of immunotherapy with preoperative neoadjuvant treatment modalities is expected to further achieve tumor downstaging,pathological remission,and radical resection.This also makes it possible for more patients to undergo gastric function-preserving surgery.This article aims to provide a general overview of neoadjuvant immunotherapy and gastric function-preserving surgery,and to focus on discussing the technical key points of gastric function-preserving surgery after neoadjuvant immunotherapy,including the selection of surgical timing,the scope of lymph node dissection,representative function-preserving gastric surgery.

关 键 词：胃肿瘤 新辅助治疗 免疫治疗 保功能 消化道重建 适应证 

分 类 号：R73[医药卫生—肿瘤]