Complex relationship between childhood obesity and the gut microbiota  

作　　者：Trung Nguyen Tran Thang Viet Luong Nam Van Duc Nguyen Hai Nguyen Ngoc Dang 

机构地区：[1]Department of Biotechnology,NTT Hi-Tech Institute,Nguyen Tat Thanh University,Ho Chi Minh 700000,Viet Nam [2]Department of Internal Medicine,University of Medicine and Pharmacy,Hue University,Hue 530000,Viet Nam [3]Faculty of Medicine,Duy Tan University,Da Nang 550000,Viet Nam

出　　处：《World Journal of Clinical Pediatrics》2025年第2期214-220,共7页世界临床儿科杂志(英文)

摘　　要：Recently,the gut microbiota has been identified as a significant risk factor associated with metabolic disorders related to obesity.Advances in high-throu-ghput sequencing technology have clarified the relationship between childhood obesity and changes in the gut microbiota.This commentary focuses on analyzing the study by Li et al,which utilized 16S rRNA molecular markers to compare differences in gut microbiota between obese and normal-weight children.Additionally,the review by Pan et al is referenced to supplement perspectives and evaluate the findings of this study.We also analyze the strengths and limitations of the original study and suggest potential research directions to elucidate the complex relationship between gut microbiota and childhood obesity,thereby providing a scientific basis for developing effective prevention and treatment strategies.

关 键 词：16S rRNA sequencing Bacterial composition Childhood obesity Gut microbiota FIRMICUTES BACTEROIDETES 

分 类 号：R57[医药卫生—消化系统]