Role of transcranial magnetic stimulation in the management of trichotillomania:A systematic review  

作　　者：Sujita Kumar Kar Babli Kumari Rini Joseph Surobhi Chatterjee Mohita Joshi Aditya Agrawal 

机构地区：[1]Department of Psychiatry,King George's Medical University,Lucknow 226003,Uttar Pradesh,India [2]Department of Psychiatry,National Institute of Mental Health and Neurosciences,Bengaluru 560029,Karnataka,India [3]Department of Psychiatry,All India Institute of Medical Sciences,Mangalagiri 522503,Andhra Pradesh,India [4]Department of Psychiatry,Dr.Ram Manohar Lohiya Institute of Medical Sciences,Lucknow 226010,Uttar Pradesh,India

出　　处：《World Journal of Meta-Analysis》2025年第1期1-10,共10页世界荟萃分析杂志(英文)

摘　　要：BACKGROUND Trichotillomania is a challenging to treat psychiatric disorder,with limited evidence for pharmacotherapy.Treatment typically involves medication,cognitive behavioral therapy,and behavioral interventions.Recently,transcranial magnetic stimulation(TMS)has emerged as a potential treatment strategy.AIM To assess the role of TMS in treating trichotillomania.METHODS A systematic search using specific terms was done in PubMed and Scopus databases for articles published until May 17,2024,related to trichotillomania and TMS.The search included randomized controlled trials,open-label studies,case series,case reports,and retrospective chart reviews,following the Preferred Items for Systematic Reviews and Meta-Analysis guideline.RESULTS We identified 32 articles(6 in PubMed and 26 in Scopus).After removing duplicates and articles that did not meet the selection criteria,we conducted a final analysis of four articles.These included one retrospective study,two case series,and one case study,with a total of 22 patients diagnosed with trichotillomania enrolled across all four studies.The brain areas targeted were the supplementary motor area(SMA),pre-SMA,and left dorsolateral prefrontal cortex.The studies reported an improvement in the severity of symptoms of trichotillomania in the majority of patients with negligible side effects.Nevertheless,it is important to note that the existing studies are mostly of low to moderate quality.CONCLUSION Early evidence suggests repetitive TMS and accelerated continuous theta burst stimulation can help treat trichotillomania adjunctively to other treatments.

关 键 词：NEUROMODULATION Transcranial magnetic stimulation Theta burst stimulation TRICHOTILLOMANIA Systematic review 

分 类 号：R74[医药卫生—神经病学与精神病学]